The study of the origin and implications of fatigue in exercise has been widely investigated,
but not completely understood given the complex multifactorial mechanisms involved. Then …

During exercise, there is a progressive reduction in the ability to produce muscle forces.
Processes within the nervous system, as well as within the muscles contribute to this fatigue …

Neuromuscular fatigue compromises exercise performance and is determined by central
and peripheral mechanisms. Interactions between the two components of fatigue can occur …

Rating of perceived effort (RPE) scales are the most frequently used single-item scales in
exercise science. They offer an easy and useful way to monitor and prescribe exercise …

New Findings What is the central question of this study? Can physiological concentrations of
metabolite combinations evoke sensations of fatigue and pain when injected into skeletal …

Group III and IV muscle afferents originating in exercising limb muscle play a significant role
in the development of fatigue during exercise in humans. Feedback from these sensory …

Endurance performance involves the prolonged maintenance of constant or self-regulated
power/velocity or torque/force. While the impact of numerous determinants of endurance …

The term fatigue is used to describe a distressing and persistent symptom of physical and/or
mental tiredness in certain clinical populations, with distinct but ultimately complex …

This review integrates from the single muscle fibre to exercising human the current
understanding of the role of skeletal muscle for whole-body potassium (K+) regulation, and …

The study of fatigue and the factors that limit, or regulate, exercise performance has
captivated scientists for centuries, but a thorough explanation of the etiology of this condition …