Diet and depression: exploring the biological mechanisms of action

W Marx, M Lane, M Hockey, H Aslam, M Berk… - Molecular …, 2021 - nature.com
The field of nutritional psychiatry has generated observational and efficacy data supporting a
role for healthy dietary patterns in depression onset and symptom management. To guide …

[HTML][HTML] Western diet as a trigger of Alzheimer's disease: From metabolic syndrome and systemic inflammation to neuroinflammation and neurodegeneration

A Więckowska-Gacek, A Mietelska-Porowska… - Ageing research …, 2021 - Elsevier
An excess of saturated fatty acids and simple sugars in the diet is a known environmental
risk factor of Alzheimer's disease (AD) but the holistic view of the interacting processes …

[HTML][HTML] Nutritional psychiatry: Towards improving mental health by what you eat

RAH Adan, EM van der Beek, JK Buitelaar… - European …, 2019 - Elsevier
Does it matter what we eat for our mental health? Accumulating data suggests that this may
indeed be the case and that diet and nutrition are not only critical for human physiology and …

Diseases, disorders, and comorbidities of interoception

B Bonaz, RD Lane, ML Oshinsky, PJ Kenny… - Trends in …, 2021 - cell.com
Interoception, the sense of the body's internal physiological state, underpins homeostatic
reflexes, motivational states, and sensations contributing to emotional experiences. The …

[HTML][HTML] Hippocampal function is impaired by a short-term high-fat diet in mice: Increased blood–brain barrier permeability and neuroinflammation as triggering events

GC de Paula, HS Brunetta, DF Engel… - Frontiers in …, 2021 - frontiersin.org
Worldwide, and especially in Western civilizations, most of the staple diets contain high
amounts of fat and refined carbohydrates, leading to an increasing number of obese …

[HTML][HTML] Heart-rate variability: a biomarker to study the influence of nutrition on physiological and psychological health?

HA Young, D Benton - Behavioural pharmacology, 2018 - journals.lww.com
As the influence of diet on health may take place over a period of decades, there is a need
for biomarkers that help to identify those aspects of nutrition that have either a positive or a …

[HTML][HTML] Diet, inflammation and the gut microbiome: mechanisms for obesity-associated cognitive impairment

SJ Leigh, MJ Morris - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2020 - Elsevier
Poor diet and obesity are associated with cognitive impairment throughout adulthood, and
increased dementia risk in aging. Here we review the current literature interrogating the …

Perineuronal nets: plasticity, protection, and therapeutic potential

AC Reichelt, DJ Hare, TJ Bussey, LM Saksida - Trends in neurosciences, 2019 - cell.com
The relationship between neurons and perineuronal nets (PNNs) is attracting attention as a
central mechanism controlling brain plasticity. In the cortex, PNNs primarily surround …

[HTML][HTML] Obesity-induced brain neuroinflammatory and mitochondrial changes

LO Schmitt, JM Gaspar - Metabolites, 2023 - mdpi.com
Obesity is defined as abnormal and excessive fat accumulation, and it is a risk factor for
developing metabolic and neurodegenerative diseases and cognitive deficits. Obesity is …

Adolescent obesity and dietary decision making—a brain-health perspective

CJ Lowe, JB Morton, AC Reichelt - The Lancet Child & Adolescent …, 2020 - thelancet.com
Adolescence represents a key period of brain development underpinned by the ongoing
maturation of the prefrontal cortex—a brain region involved in the regulation of behaviour …