[HTML][HTML] The role of inflammation in autoimmune disease: a therapeutic target

Y Xiang, M Zhang, D Jiang, Q Su, J Shi - Frontiers in Immunology, 2023 - frontiersin.org
Autoimmune diseases (AIDs) are immune disorders whose incidence and prevalence are
increasing year by year. AIDs are produced by the immune system's misidentification of self …

[HTML][HTML] The dual face of microglia (M1/M2) as a potential target in the protective effect of nutraceuticals against neurodegenerative diseases

SF Darwish, AMM Elbadry, AS Elbokhomy… - Frontiers in …, 2023 - frontiersin.org
The pathophysiology of different neurodegenerative illnesses is significantly influenced by
the polarization regulation of microglia and macrophages. Traditional classifications of …

[HTML][HTML] Ginger intake suppresses neutrophil extracellular trap formation in autoimmune mice and healthy humans

RA Ali, VC Minarchick, M Zahavi, CE Rysenga… - JCI insight, 2023 - ncbi.nlm.nih.gov
We previously reported that treatment of mice with 6-gingerol, the most abundant
phytochemical in ginger root, leads to phosphodiesterase inhibition that counteracts …

[HTML][HTML] Anti-inflammatory and antioxidant activity of ursolic acid: a systematic review and meta-analysis

M Zhao, F Wu, Z Tang, X Yang, Y Liu… - Frontiers in …, 2023 - frontiersin.org
Introduction: There is currently evidence suggesting that ursolic acid may exert a favorable
influence on both anti-inflammatory and antioxidant impact. Nevertheless, the anti …

[HTML][HTML] Triterpenes as potential drug candidates for rheumatoid arthritis treatment

C Faustino, L Pinheiro, N Duarte - Life, 2023 - mdpi.com
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease characterized by
joint inflammation, swelling and pain. Although RA mainly affects the joints, the disease can …

Natural compounds as potential therapeutic candidates for multiple sclerosis: emerging preclinical evidence

J Yuan, Y Tao, M Wang, F Huang, X Wu - Phytomedicine, 2023 - Elsevier
Background Multiple sclerosis is a chronic neurodegenerative disease, with main
characteristics of pathological inflammation, neural damage and axonal demyelination …

Epigallocatechin gallate: A multifaceted molecule for neurological disorders and neurotropic viral infections

A Rani, V Saini, P Patra, T Prashar… - ACS Chemical …, 2023 - ACS Publications
Epigallocatechin-3-gallate (EGCG), a polyphenolic moiety found in green tea extracts,
exhibits pleiotropic bioactivities to combat many diseases including neurological ailments …

[HTML][HTML] Modulation of acute intestinal inflammation by dandelion polysaccharides: An in-depth analysis of antioxidative, anti-inflammatory effects and gut microbiota …

Z Li, X Li, P Shi, P Li, Y Fu, G Tan, J Zhou… - International Journal of …, 2024 - mdpi.com
Acute colitis is a complex disease that can lead to dysregulation of the gut flora, inducing
more complex parenteral diseases. Dandelion polysaccharides (DPSs) may have potential …

Mechanistic insights into inhibition of CCL2-guided leukocyte recruitment by oxyresveratrol and its derivatives

DK Tripathi, N Nagar, G Naidu, V Kumar, P Roy… - Journal of Molecular …, 2024 - Elsevier
Inflammatory responses are the outcomes of coordinated interactions amongst chemokines
and their exclusive non-negotiable counterparts such as glycosaminoglycans and GPCRs …

[HTML][HTML] Evaluation of the immune-modulatory, anti-oxidant, proliferative, and anti-apoptotic effects of nano-silymarin on mesenchymal stem cells isolated from multiple …

FL Arab, F Yousefi, MR Jaafari, A Rajabian… - Journal of Functional …, 2024 - Elsevier
Silymarin (SL) has a long history of use for the treatment of a variety of diseases, but several
limitations, such as poor bioavailability and negligible solubility, have restricted its …