Quantitative interactome analysis with chemical cross-linking and mass spectrometry
Structural plasticity and dynamic protein–protein interactions are critical determinants of
protein function within living systems. Quantitative chemical cross-linking with mass …
protein function within living systems. Quantitative chemical cross-linking with mass …
Maize metabolome and proteome responses to controlled cold stress partly mimic early‐sowing effects in the field and differ from those of Arabidopsis
M Urrutia, M Blein‐Nicolas, S Prigent… - Plant, cell & …, 2021 - Wiley Online Library
Abstract In Northern Europe, sowing maize one‐month earlier than current agricultural
practices may lead to moderate chilling damage. However, studies of the metabolic …
practices may lead to moderate chilling damage. However, studies of the metabolic …
Identification of candidate casein kinase 2 substrates in mitosis by quantitative phosphoproteomics
SF Rusin, ME Adamo, AN Kettenbach - Frontiers in cell and …, 2017 - frontiersin.org
Protein phosphorylation is a crucial regulatory mechanism that controls many aspects of
cellular signaling. Casein kinase 2 (CK2), a constitutively expressed and active kinase …
cellular signaling. Casein kinase 2 (CK2), a constitutively expressed and active kinase …
Aurora B opposes PP1 function in mitosis by phosphorylating the conserved PP1-binding RVxF motif in PP1 regulatory proteins
Protein phosphatase 1 (PP1) is a highly conserved protein phosphatase that performs most
of the serine-and threonine-dephosphorylation reactions in eukaryotes and opposes the …
of the serine-and threonine-dephosphorylation reactions in eukaryotes and opposes the …
Quantitative interactome analysis reveals a chemoresistant edgotype
Chemoresistance is a common mode of therapy failure for many cancers. Tumours develop
resistance to chemotherapeutics through a variety of mechanisms, with proteins serving …
resistance to chemotherapeutics through a variety of mechanisms, with proteins serving …
Multi-omics approaches unravel specific features of embryo and endosperm in rice seed germination
Seed germination and subsequent seedling growth affect the final yield and quality of the
crop. Seed germination is defined as a series of processes that begins with water uptake by …
crop. Seed germination is defined as a series of processes that begins with water uptake by …
Microglial TNFα orchestrates protein phosphorylation in the cortex during the sleep period and controls homeostatic sleep
Sleep intensity is adjusted by the length of previous awake time, and under tight homeostatic
control by protein phosphorylation. Here, we establish microglia as a new cellular …
control by protein phosphorylation. Here, we establish microglia as a new cellular …
Global proteomic identifies multiple cancer-related signaling pathways altered by a gut pathobiont associated with colorectal cancer
In this work, we investigated the oncogenic role of Streptococcus gallolyticus subsp.
gallolyticus (SGG), a gut bacterium associated with colorectal cancer (CRC). We showed …
gallolyticus (SGG), a gut bacterium associated with colorectal cancer (CRC). We showed …
Quantitative cross-linking/mass spectrometry to elucidate structural changes in proteins and their complexes
ZA Chen, J Rappsilber - Nature Protocols, 2019 - nature.com
Quantitative cross-linking/mass spectrometry (QCLMS/QXL-MS) probes structural changes
of proteins in solution. This method has revealed induced conformational changes …
of proteins in solution. This method has revealed induced conformational changes …
Protein dynamics in solution by quantitative crosslinking/mass spectrometry
ZA Chen, J Rappsilber - Trends in biochemical sciences, 2018 - cell.com
The dynamics of protein structures and their interactions are responsible for many cellular
processes. The rearrangements and interactions of proteins, which are often transient, occur …
processes. The rearrangements and interactions of proteins, which are often transient, occur …