Owing to their high extinction coefficients, long absorption wavelengths, and modification
tunable photophysical and photochemical properties, phthalocyanines (Pcs) have been …

The immune checkpoint pathway consisting of the cell membrane-bound molecule
programmed death protein 1 (PD-1) and its ligand PD-L1 has been found to mediate …

While epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) have
changed the treatment landscape for EGFR mutant (L858R and ex19del)-driven non-small …

It has recently become clear that the tumour microenvironment, and in particular the immune
system, has a crucial role in modulating tumour progression and response to therapy …

Since the molecular revolution of the 1980s, knowledge of the aetiology of cancer has
increased considerably, which has led to the discovery and development of targeted …

This paper intended to explore and discover recent therapeutic agents in the area of
medicinal chemistry for the treatment of various diseases. Heterocyclic compounds …

Chemotherapeutic and cytotoxic drugs are widely used in the treatment of cancer. In spite of
the improvements in the life quality of patients, their effectiveness is compromised by several …

Quinoxaline is a fused heterocycle ring template present in diverse pharmacophore and
widely used in medicinal chemistry. Owing to its vast pharmaceutical profile, several …

A strategy for the synthesis of quinazolinones via acceptorless coupling of o-
aminobenzamides with methanol has been accomplished in the presence of the metal …

Epidermal growth factor receptor (EGFR, also known as HER1) and HER2, prominent
members of receptor tyrosine kinase (RTK) superfamily, have been reported as diagnostic or …