Melanoma, the most aggressive form of cutaneous malignancy arising from melanocytes, is
frequently characterized by metastasis. Despite considerable progress in melanoma …

Pancreatic cancer is a highly malignant and incurable disease, characterized by its
aggressive nature and high fatality rate. The most common type is pancreatic ductal …

Pancreatic cancer is one of the common malignant tumors of the digestive system and is
known as the “king of cancers”. It is extremely difficult to diagnose at an early stage, the …

Immunosuppression is a hallmark of pancreatic ductal adenocarcinoma (PDAC),
contributing to early metastasis and poor patient survival. Compared to the localized tumors …

Recent advances in drug delivery technologies utilizing a variety of carriers have resulted in
a paradigm shift in the current approach to diagnosis and therapy. Mesoporous silica …

In addition to the contribution of cancer cells, the solid tumor microenvironment (TME) has a
critical role in determining tumor expansion, antitumor immunity, and the response to …

Over the past two decades, multidisciplinary investigations into the development of
nanoparticles for medical applications have continually increased. However, nanoparticles …

Pancreatic cancer is one of the harshest and most challenging cancers to treat, often labeled
as incurable. Chemotherapy continues to be the most popular treatment yet yields a very …

In clinical settings, cancer vaccines as monotherapies have displayed limited success
compared to other cancer immunotherapeutic treatments. Nanoscale formulations have the …

Chimeric antigen receptor (CAR) T cell therapy has achieved unprecedented clinical
success against hematologic malignancies. However, the transition of CAR-T cell therapies …