Toward hijacking bioelectricity in cancer to develop new bioelectronic medicine

AJ Robinson, A Jain, HG Sherman… - Advanced …, 2021 - Wiley Online Library
Bioelectronic medicine is a treatment modality that uses electricity to treat disease by
altering the body's electrical communication systems. All cells are electrically active, in that …

Bioelectronic medicines: Therapeutic potential and advancements in next-generation cancer therapy

AK Singh, R Awasthi, R Malviya - … et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
Bioelectronic medicine has tremendous potential in biomedical sector including oncology
research, research on biomechanical and chemical properties of cells and biomaterials …

Divergent expression of hypoxia response systems under deoxygenation in reef‐forming corals aligns with bleaching susceptibility

R Alderdice, DJ Suggett, A Cárdenas… - Global Change …, 2021 - Wiley Online Library
Exposure of marine life to low oxygen is accelerating worldwide via climate change and
localized pollution. Mass coral bleaching and mortality have recently occurred where reefs …

KCNN4 promotes the stemness potentials of liver cancer stem cells by enhancing glucose metabolism

J Fan, R Tian, X Yang, H Wang, Y Shi, X Fan… - International journal of …, 2022 - mdpi.com
The presence of liver cancer stem cells (LCSCs) is one of the reasons for the treatment
failure of hepatocellular carcinoma (HCC). For LCSCs, one of their prominent features is …

The distinguishing electrical properties of cancer cells

E Di Gregorio, S Israel, M Staelens, G Tankel… - Physics of life …, 2022 - Elsevier
In recent decades, medical research has been primarily focused on the inherited aspect of
cancers, despite the reality that only 5–10% of tumours discovered are derived from genetic …

The role of potassium channels in tumours of the gastrointestinal tract: a focus on the human ether‐à‐go‐go related gene 1 channels

A Arcangeli, C Duranti, J Iorio… - The Journal of …, 2023 - Wiley Online Library
Potassium channels are often dysregulated in tumours of the gastrointestinal (GI) tract.
Among them, the voltage‐dependent channel KV11. 1, also known as human ether‐à‐go …

Potassium channels, glucose metabolism and glycosylation in cancer cells

A Wawrzkiewicz-Jałowiecka, A Lalik… - International Journal of …, 2023 - mdpi.com
Potassium channels emerge as one of the crucial groups of proteins that shape the biology
of cancer cells. Their involvement in processes like cell growth, migration, or electric …

Remotely disturbing bioelectrical homeostasis by nanoparticle-enabled intracellular electrical stimulation for wireless cancer therapy

C Xiao, L Fan, C Li, L Zhou, C Deng, R Fu, D Chen… - Nano Today, 2024 - Elsevier
Bioelectrical homeostasis plays critical roles in biological processes, but disturbing it for
cancer therapy remains challenging due to the difficulty in electrically controlling cancer …

The role of potassium in depth profiling of the tumor border in bone-invasive oral cancer using laser-induced breakdown spectroscopy (LIBS): A pilot study

P Winnand, KO Boernsen, M Ooms, M Heitzer… - Journal of Cancer …, 2023 - Springer
Purpose Microscopic tumor spread beyond the macroscopically visible tumor mass in bone
represents a major risk in surgical oncology, where the spatial complexity of bony resection …

Disrupting Na+ ion homeostasis and Na+/K+ ATPase activity in breast cancer cells directly modulates glycolysis in vitro and in vivo

AM Michaels, A Zoccarato, Z Hoare, G Firth… - Cancer & …, 2024 - Springer
Background Glycolytic flux is regulated by the energy demands of the cell. Upregulated
glycolysis in cancer cells may therefore result from increased demand for adenosine …