[PDF][PDF] Therapeutic Anti-TNF [alpha] Antibodies Differentially Affect Leishmania Infection of Primary Human Macrophages

K Arens - 2018 - openscience.ub.uni-mainz.de
Excessive production of the pro-inflammatory cytokine tumor necrosis factor α (TNFα) is
associated with the pathophysiology of human autoimmune diseases. As a consequence …

[PDF][PDF] Journal of Immunobiology

JA Fiuza, ST Gaze - 2018 - researchgate.net
Among the clinical forms of leishmaniasis, visceral leishmaniasis is the most debilitating
clinical form because it compromises mainly liver and spleen in the host. The immune …

Canine leishmaniasis: the role of hepatocytes and Kupffer cells during Leishmania infantum infection

MAV Rodrigues - 2017 - search.proquest.com
Canine leishmaniasis (CanL) is a zoonotic disease caused by Leishmania infantum, a
protozoan parasite transmitted by sand flies. The liver is a vital and major metabolic organ …

[PDF][PDF] Identification and Characterization of new candidate proteins for vaccination against leishmaniasis using a novel approach

O Shimony - 2016 - researchgate.net
Leishmaniasis is a diverse group of diseases caused by an obligate intracellular protozoan
parasite, Leishmania. These parasites are transmitted by the bite of female Phlebotomine …

Perfil de citocinas do padrão Th1, Th2, Th17 eo estado redox de indivíduos com leishmaniose visceral pré e pós tratamento

FCT Carvalho - 2016 - repositorio.unesp.br
A leishmaniose visceral (LV) é causada pelos protozoários intracelulares obrigatórios
pertencentes ao complexo Leishamania donovani (L. donovani). O sucesso na cura da LV …

[PDF][PDF] Studies on Immunological Responses to Parasite Surface Antigen as a Potential Vaccine Candidate against Human Leishmaniasis and Estimation of …

H Kaushal - 2016 - dspace.bits-pilani.ac.in
At present, there is no licensed vaccine available against any form of human leishmaniasis,
although, the development of an anti-Leishmania vaccine has been a longterm goal …

Antigenicity, Immunogenicity and Protective Efficacy of Three Proteins Expressed in the Promastigote and Amastigote Stages of Leishmania infantum against Visceral …

V Tamietti Martins, M Soto, EA Ferranz Coelho - 2015 - digital.csic.es
In the present study, two Leishmania infantum hypothetical proteins present in the
amastigote stage, LiHyp1 and LiHyp6, were combined with a promastigote protein, IgE …

[PDF][PDF] Papel dos receptores Toll-Like 2 e 4 do estado nutricional em pacientes com leishmaniose visceral

M Gatto - 2014 - repositorio.unesp.br
A leishmaniose visceral (LV) é um problema emergente de saúde pública, sendo uma das
principais doenças negligenciadas no Brasil e no mundo. É causada por L. donovanie L …

[PDF][PDF] In Vitro Evaluation of a Soluble Leishmania Promastigote

R Chamakh-Ayari, R Bras-Gonçalves, N Bahi-Jaber… - 2014 - academia.edu
Abstract PSA (Promastigote Surface Antigen) belongs to a family of membrane-bound and
secreted proteins present in several Leishmania (L.) species. PSA is recognized by human …

Uso de Leishmania donovani geneticamente modificada (LdCen-/-) como modelo de vacina protetora contra a leishmaniose visceral canina

JA Fiuza - 2013 - arca.fiocruz.br
A leishmaniose visceral zoonótica (LVZ), causada pelo parasito intracelular Leishmania
infantum, é uma doença tropical negligenciada que pode ser fatal quando não tratada. Os …