The year 2017 marks the twentieth anniversary of terpenoid cyclase structural biology: a trio
of terpenoid cyclase structures reported together in 1997 were the first to set the foundation …

Beginning with the discovery of penicillin by Alexander Fleming in the late 1920s, antibiotics
have revolutionized the field of medicine. They have saved millions of lives each year …

Odoriferous terpene metabolites of bacterial origin have been known for many years. In
genome-sequenced Streptomycetaceae microorganisms, the vast majority produces the …

Covering: up to 2015 This review summarises the accumulated knowledge about
characterised bacterial terpene cyclases. The structures of identified products and of …

Covering: up to mid-2020 Terpenoids, also called isoprenoids, are the largest and most
structurally diverse family of natural products. Found in all domains of life, there are over 80 …

Covering: up to mid-2009 The phylum Actinobacteria hosts diverse high G+ C, Gram-
positive bacteria that have evolved a complex chemical language of natural product …

Covering: 1990 to 2006 This review describes volatiles released into the air by bacteria
growing on defined media. Their occurrence, function, and biosynthesis are discussed, and …

To construct a versatile model host for heterologous expression of genes encoding
secondary metabolite biosynthesis, the genome of the industrial microorganism …

The majority of all biologically caused taste-and-odor outbreaks in drinking water
characterized worldwide are caused by microbial production of ()-geosmin [()-(4S, 4aS, 8aR) …

We determined the complete genome sequence of Streptomyces griseus IFO 13350, a soil
bacterium producing an antituberculosis agent, streptomycin, which is the first …