[HTML][HTML] Role of iodide metabolism in physiology and cancer

A De la Vieja, P Santisteban - Endocrine-related cancer, 2018 - erc.bioscientifica.com
Iodide (I−) metabolism is crucial for the synthesis of thyroid hormones (THs) in the thyroid
and the subsequent action of these hormones in the organism. I− is principally transported …

Iodine Status in the Colombian Population and the Impact of Universal Salt Iodization: A Double‐Edged Sword?

H Vargas-Uricoechea… - Journal of nutrition …, 2019 - Wiley Online Library
Iodine deficiency and iodine excess have severe consequences on human health and have
been associated with the presence of goiter, hypothyroidism, hyperthyroidism, thyroid …

[HTML][HTML] Intrathyroidal feedforward and feedback network regulating thyroid hormone synthesis and secretion

L Jing, Q Zhang - Frontiers in Endocrinology, 2022 - frontiersin.org
Thyroid hormones (THs), including T4 and T3, are produced and released by the thyroid
gland under the stimulation of thyroid-stimulating hormone (TSH). The homeostasis of THs is …

[HTML][HTML] Redox Homeostasis in Thyroid Cancer: Implications in Na+/I Symporter (NIS) Regulation

J Cazarin, C Dupuy, D Pires de Carvalho - International journal of …, 2022 - mdpi.com
Radioiodine therapy (RAI) is a standard and effective therapeutic approach for differentiated
thyroid cancers (DTCs) based on the unique capacity for iodide uptake and accumulation of …

Effects of repeated potassium iodide administration on genes involved in synthesis and secretion of thyroid hormone in adult male rat

D Lebsir, L Manens, S Grison, P Lestaevel… - Molecular and cellular …, 2018 - Elsevier
Background A single dose of potassium iodide (KI) is recommended to reduce the risk of
thyroid cancer during nuclear accidents. However in case of prolonged radioiodine …

Effects of 2-iodohexadecanal in the physiology of thyroid cells

LE Rossich, L Thomasz, JP Nicola, M Nazar… - Molecular and cellular …, 2016 - Elsevier
Iodide has direct effects on thyroid function. Several iodinated lipids are biosynthesized by
the thyroid and they were postulated as intermediaries in the action of iodide. Among them …

[HTML][HTML] Review of the PRIODAC project on thyroid protection from radioactive iodine by repeated iodide intake in individuals aged 12+

JC Martin, T Pourcher, G Phan… - European Thyroid …, 2024 - etj.bioscientifica.com
Background Intake of potassium iodide (KI) reduces the accumulation of radioactive iodine
in the thyroid gland in the event of possible contamination by radioactive iodine released …

Excess iodide-induced reactive oxygen species elicit iodide efflux via β-tubulin-associated ClC-3 in thyrocytes

M Yu, Y Wei, P Wang, Z Deng, J Mao, L Zhu… - Biochemical …, 2022 - portlandpress.com
Iodide (I−) is crucial to thyroid function, and its regulation in thyrocytes involves ion
transporters and reactive oxygen species (ROS). However, the extent of 2Cl−/H+ exchanger …

Upregulation of TSHR, TTF‐1, and PAX8 in nodular goiter is associated with iodine deficiency in the follicular lumen

H Huang, L Chen, B Liang, H Cai… - International Journal of …, 2016 - Wiley Online Library
Objective. It has been testified that iodine regulates thyroid function by controlling thyroid‐
restricted genes expression and is closely related to diffuse goiter and thyroid dysfunction …

Análisis del estado poblacional del yodo en Colombia y la necesidad de modificar los niveles de yodación universal de la sal

HV Uricoechea, JM Palacios… - Revista Colombiana de …, 2020 - revistaendocrino.org
Iodine deficiency and iodine excess have severe consequences on human health, and have
been associated with the presence of goiter, hypothyroidism, hyperthyroidism, thyroid …