Intrathyroidal feedforward and feedback network regulating thyroid hormone synthesis and secretion
L Jing, Q Zhang - Frontiers in endocrinology, 2022 - frontiersin.org
Thyroid hormones (THs), including T4 and T3, are produced and released by the thyroid
gland under the stimulation of thyroid-stimulating hormone (TSH). The homeostasis of THs is …
gland under the stimulation of thyroid-stimulating hormone (TSH). The homeostasis of THs is …
Role of iodide metabolism in physiology and cancer
A De la Vieja, P Santisteban - Endocrine-related cancer, 2018 - erc.bioscientifica.com
Iodide (I−) metabolism is crucial for the synthesis of thyroid hormones (THs) in the thyroid
and the subsequent action of these hormones in the organism. I− is principally transported …
and the subsequent action of these hormones in the organism. I− is principally transported …
Iodine Status in the Colombian Population and the Impact of Universal Salt Iodization: A Double‐Edged Sword?
H Vargas-Uricoechea… - Journal of nutrition …, 2019 - Wiley Online Library
Iodine deficiency and iodine excess have severe consequences on human health and have
been associated with the presence of goiter, hypothyroidism, hyperthyroidism, thyroid …
been associated with the presence of goiter, hypothyroidism, hyperthyroidism, thyroid …
Redox Homeostasis in Thyroid Cancer: Implications in Na+/I− Symporter (NIS) Regulation
J Cazarin, C Dupuy, D Pires de Carvalho - International journal of …, 2022 - mdpi.com
Radioiodine therapy (RAI) is a standard and effective therapeutic approach for differentiated
thyroid cancers (DTCs) based on the unique capacity for iodide uptake and accumulation of …
thyroid cancers (DTCs) based on the unique capacity for iodide uptake and accumulation of …
Effects of repeated potassium iodide administration on genes involved in synthesis and secretion of thyroid hormone in adult male rat
D Lebsir, L Manens, S Grison, P Lestaevel… - Molecular and cellular …, 2018 - Elsevier
Background A single dose of potassium iodide (KI) is recommended to reduce the risk of
thyroid cancer during nuclear accidents. However in case of prolonged radioiodine …
thyroid cancer during nuclear accidents. However in case of prolonged radioiodine …
Effects of 2-iodohexadecanal in the physiology of thyroid cells
LE Rossich, L Thomasz, JP Nicola, M Nazar… - Molecular and cellular …, 2016 - Elsevier
Iodide has direct effects on thyroid function. Several iodinated lipids are biosynthesized by
the thyroid and they were postulated as intermediaries in the action of iodide. Among them …
the thyroid and they were postulated as intermediaries in the action of iodide. Among them …
Review of the PRIODAC project on thyroid protection from radioactive iodine by repeated iodide intake in individuals aged 12+
JC Martin, T Pourcher, G Phan… - European Thyroid …, 2024 - etj.bioscientifica.com
Background Intake of potassium iodide (KI) reduces the accumulation of radioactive iodine
in the thyroid gland in the event of possible contamination by radioactive iodine released …
in the thyroid gland in the event of possible contamination by radioactive iodine released …
Protection and safety of a repeated dosage of KI for iodine thyroid blocking during pregnancy
H Gaouaoui-Azouaou, B L'Homme… - Journal of …, 2022 - iopscience.iop.org
In case of nuclear power plant accidents resulting in the release of radioactive iodine (131 I)
in large amounts, a single intake of stable iodine is recommended in order to prevent 131 I …
in large amounts, a single intake of stable iodine is recommended in order to prevent 131 I …
Excess iodide-induced reactive oxygen species elicit iodide efflux via β-tubulin-associated ClC-3 in thyrocytes
M Yu, Y Wei, P Wang, Z Deng, J Mao, L Zhu… - Biochemical …, 2022 - portlandpress.com
Iodide (I−) is crucial to thyroid function, and its regulation in thyrocytes involves ion
transporters and reactive oxygen species (ROS). However, the extent of 2Cl−/H+ exchanger …
transporters and reactive oxygen species (ROS). However, the extent of 2Cl−/H+ exchanger …
Upregulation of TSHR, TTF‐1, and PAX8 in Nodular Goiter Is Associated with Iodine Deficiency in the Follicular Lumen
H Huang, L Chen, B Liang, H Cai… - International Journal of …, 2016 - Wiley Online Library
Objective. It has been testified that iodine regulates thyroid function by controlling thyroid‐
restricted genes expression and is closely related to diffuse goiter and thyroid dysfunction …
restricted genes expression and is closely related to diffuse goiter and thyroid dysfunction …