[HTML][HTML] Improving the study of brain-behavior relationships by revisiting basic assumptions

C Westlin, JE Theriault, Y Katsumi… - Trends in cognitive …, 2023 - cell.com
Neuroimaging research has been at the forefront of concerns regarding the failure of
experimental findings to replicate. In the study of brain-behavior relationships, past failures …

Large-scale neural recordings call for new insights to link brain and behavior

AE Urai, B Doiron, AM Leifer, AK Churchland - Nature neuroscience, 2022 - nature.com
Neuroscientists today can measure activity from more neurons than ever before, and are
facing the challenge of connecting these brain-wide neural recordings to computation and …

Global waves synchronize the brain's functional systems with fluctuating arousal

RV Raut, AZ Snyder, A Mitra, D Yellin, N Fujii… - Science …, 2021 - science.org
We propose and empirically support a parsimonious account of intrinsic, brain-wide
spatiotemporal organization arising from traveling waves linked to arousal. We hypothesize …

Neuromodulation of brain state and behavior

DA McCormick, DB Nestvogel… - Annual review of …, 2020 - annualreviews.org
Neural activity and behavior are both notoriously variable, with responses differing widely
between repeated presentation of identical stimuli or trials. Recent results in humans and …

[HTML][HTML] Vagal sensory neurons mediate the Bezold–Jarisch reflex and induce syncope

JW Lovelace, J Ma, S Yadav, K Chhabria, H Shen… - Nature, 2023 - nature.com
Visceral sensory pathways mediate homeostatic reflexes, the dysfunction of which leads to
many neurological disorders. The Bezold–Jarisch reflex (BJR), first described, in 1867, is a …

Facemap: a framework for modeling neural activity based on orofacial tracking

A Syeda, L Zhong, R Tung, W Long, M Pachitariu… - Nature …, 2024 - nature.com
Recent studies in mice have shown that orofacial behaviors drive a large fraction of neural
activity across the brain. To understand the nature and function of these signals, we need …

Not so spontaneous: Multi-dimensional representations of behaviors and context in sensory areas

L Avitan, C Stringer - Neuron, 2022 - cell.com
Sensory areas are spontaneously active in the absence of sensory stimuli. This
spontaneous activity has long been studied; however, its functional role remains largely …

Behavioral decomposition reveals rich encoding structure employed across neocortex in rats

B Mimica, T Tombaz, C Battistin, JG Fuglstad… - Nature …, 2023 - nature.com
The cortical population code is pervaded by activity patterns evoked by movement, but it
remains largely unknown how such signals relate to natural behavior or how they might …

Estimation of current and future physiological states in insular cortex

Y Livneh, AU Sugden, JC Madara, RA Essner… - Neuron, 2020 - cell.com
Interoception, the sense of internal bodily signals, is essential for physiological homeostasis,
cognition, and emotions. While human insular cortex (InsCtx) is implicated in interoception …

Ultra-slow oscillations in fMRI and resting-state connectivity: neuronal and vascular contributions and technical confounds

PJ Drew, C Mateo, KL Turner, X Yu, D Kleinfeld - Neuron, 2020 - cell.com
Summary Ultra-slow,∼ 0.1-Hz variations in the oxygenation level of brain blood are widely
used as an fMRI-based surrogate of" resting-state" neuronal activity. The temporal …