Platelets are a major player and represent a therapeutic opportunity in systemic lupus erythematosus
M Robert, M Scherlinger - Joint Bone Spine, 2024 - Elsevier
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by immune
dysregulation and organ injury with a premature mortality due to cardiovascular diseases …
dysregulation and organ injury with a premature mortality due to cardiovascular diseases …
Alternative platelet differentiation pathways initiated by nonhierarchically related hematopoietic stem cells
J Carrelha, S Mazzi, A Winroth… - Nature …, 2024 - nature.com
Rare multipotent stem cells replenish millions of blood cells per second through a time-
consuming process, passing through multiple stages of increasingly lineage-restricted …
consuming process, passing through multiple stages of increasingly lineage-restricted …
Identification of platelet-related subtypes and diagnostic markers in pediatric Crohn's disease based on WGCNA and machine learning
D Tang, Y Huang, Y Che, C Yang, B Pu, S Liu… - Frontiers in …, 2024 - frontiersin.org
Background The incidence of pediatric Crohn's disease (PCD) is increasing worldwide
every year. The challenges in early diagnosis and treatment of PCD persist due to its …
every year. The challenges in early diagnosis and treatment of PCD persist due to its …
Impaired bisecting GlcNAc reprogrammed M1 polarization of macrophage
The functions of macrophages are governed by distinct polarization phenotypes, which can
be categorized as either anti-tumor/M1 type or pro-tumor/M2 type. Glycosylation is known to …
be categorized as either anti-tumor/M1 type or pro-tumor/M2 type. Glycosylation is known to …
Platelet activation through CD62P and platelet–monocyte complexes contribute to exacerbation of mucosal inflammation in patients with ulcerative colitis
Y Sano, T Tomiyama, N Yagi, Y Ito, Y Honzawa… - 2024 - researchsquare.com
Ulcerative colitis (UC) is a refractory, chronic inflammatory bowel disease of unknown
etiology. Although platelets are activated in UC, their relevance in pathophysiology remains …
etiology. Although platelets are activated in UC, their relevance in pathophysiology remains …
Serum LGALS3BP is a potential biomarker for interstitial lung disease in dermatomyositis
L Huang, W Zhou, Y Jiang, H Zhu, Y Lao, X Huang… - 2024 - researchsquare.com
Objectives To assess the relationship between serum LGALS3BP levels and clinical
features in patients with dermatomyositis (DM), emphasizing interstitial lung disease (ILD) …
features in patients with dermatomyositis (DM), emphasizing interstitial lung disease (ILD) …