Altering the tropism of lentiviral vectors through pseudotyping

J Cronin, XY Zhang, J Reiser - Current gene therapy, 2005 - ingentaconnect.com
The host range of retroviral vectors including lentiviral vectors can be expanded or altered
by a process known as pseudotyping. Pseudotyped lentiviral vectors consist of vector …

Practical uses for ecdysteroids in mammals including humans: and update

R Lafont, L Dinan - Journal of insect science, 2003 - academic.oup.com
Ecdysteroids are widely used as inducers for gene-switch systems based on insect
ecdysteroid receptors and genes of interest placed under the control of ecdysteroid …

Gene therapy progress and prospects: development of improved lentiviral and retroviral vectors–design, biosafety, and production

PL Sinn, SL Sauter, PB McCray - Gene therapy, 2005 - nature.com
Replication defective vectors derived from simple retroviruses or the more complex
genomes of lentiviruses continue to offer the advantages of long-term expression, cell and …

Lentiviral vectors: optimization of packaging, transduction and gene expression

C Delenda - The Journal of Gene Medicine: A cross …, 2004 - Wiley Online Library
Gene transfer vectors based on retroviruses including oncogenic retroviruses and
lentiviruses provide effective means for the delivery, integration and expression of …

Lentiviral vectors for cancer immunotherapy: transforming infectious particles into therapeutics

K Breckpot, JL Aerts, K Thielemans - Gene therapy, 2007 - nature.com
Lentiviral vectors have emerged as promising tools for both gene therapy and
immunotherapy purposes. They exhibit several advantages over other viral systems in that …

Dendritic cells for active anti-cancer immunotherapy: targeting activation pathways through genetic modification

K Breckpot, D Escors - Endocrine, Metabolic & Immune …, 2009 - ingentaconnect.com
Tumour immunotherapy has become a treatment modality for cancer, harnessing the
immune system to recognize and eradicate tumour cells specifically. It is based on the …

Lentiviral vectors

AML Lever - … , Applications and Regulations: From Laboratory to …, 1999 - Wiley Online Library
Lentiviruses are a subfamily of retroviruses infecting primate and non‐primate hosts. They
have multiple spliced RNA species and several small regulatory proteins that allow …

Recent progress in lentiviral vector mass production

S Ansorge, O Henry, A Kamen - Biochemical engineering journal, 2010 - Elsevier
Lentiviral vectors (LV) are promising tools for gene and cell therapy. They are presently used
in several clinical trials as in vivo or ex vivo gene delivery vectors. However their mass …

Efficient large volume lentiviral vector production using flow electroporation

SR Witting, LH Li, A Jasti, C Allen, K Cornetta… - Human gene …, 2012 - liebertpub.com
Lentiviral vectors are beginning to emerge as a viable choice for human gene therapy. Here,
we describe a method that combines the convenience of a suspension cell line with a …

[图书][B] Lentiviral gene therapy vectors: challenges and future directions

HA Tomás, AF Rodrigues, PM Alves, AS Coroadinha - 2013 - intechopen.com
Lentiviral vectors (LV) are efficient vehicles for gene transfer in mammalian cells due to their
capacity to stably express a gene of interest in non-dividing and dividing cells. Their use has …