Background: The cartilage tissue lacks blood vessels, which is composed of chondrocytes
and ECM. Due to this vessel-less structure, it is difficult to repair cartilage tissue damages …

Osteoarthritis (OA), a chronic debilitating joint disease affecting hundreds of million people
globally, is associated with significant pain and socioeconomic costs. Current treatment …

Cartilage defects and osteoarthritis are health problems which are major burdens on health
care systems globally, especially in aging populations. Cartilage is a vulnerable tissue …

Hemifacial microsomia (HFM), a rare disorder of first-and second-pharyngeal arch
development, has been linked to a point mutation in VWA1 (von Willebrand factor A domain …

Articular cartilage allows the human body to buffer and absorb stress during normal
exercise. It is mainly composed of cartilage cells and the extracellular matrix and is …

Abnormal N-glycosylation has been shown to play an important role in the pathogenesis of
multiple diseases. However, little is known about the relationship between N-glycosylation …

Cartilages are unique in the family of connective tissues in that they contain a high
concentration of the glycosaminoglycans, chondroitin sulfate and keratan sulfate attached to …

Osteoarthritis (OA), a chronic degenerative joint disease, is the most common form of
arthritis. OA occurs when the protective cartilage that cushions the ends of bones gradually …

This review examined how Hippo cell signaling and heparan sulfate (HS)-proteoglycans
(HSPGs) regulate tissue form and function. Despite being a nonweight-bearing tissue, the …

Matrikines in kidney ageing and age-related disease : Current Opinion in Nephrology and
Hypertension Matrikines in kidney ageing and age-related disease : Current Opinion in …