Polygenic risk scores (PRSs) hold promise for disease risk assessment and prevention. The
Genomic Medicine at Veterans Affairs (GenoVA) Study is addressing three main challenges …

Polygenic inheritance is a non-Mendelian form of inheritance in which the risk of a trait,
disorder, or disease results from the combined contribution of variants from multiple genes …

Polygenic scores (PGS) can be used for risk stratification by quantifying individuals' genetic
predisposition to disease, and many potentially clinically useful applications have been …

Polygenic risk score (PRS) assessment for embryo selection (hereafter referred to as
preimplantation testing for polygenic disorder [PGT-P]) is an emerging reproductive …

The number of human disease genes has dramatically increased over the past decade,
largely fueled by ongoing advances in sequencing technologies. In parallel, the number of …

Цель. Провести валидацию и оценить точность 14 шкал генетического риска (ШГР)
сахарного диабета 2 типа (СД2), созданных ранее в других странах, на выборке …

Цель. На выборке населения двух регионов европейской части России провести
валидацию и оценить точность 15 шкал генетического риска (ШГР) ожирения …

This guidance endeavours to articulate the scientific evidence underpinning the clinical
utility of polygenic risk score in stratifying breast cancer risk, with a particular emphasis on …

Polygenic risk scores (PRSs) hold promise for disease risk assessment and prevention. The
Genomic Medicine at Veterans Affairs (GenoVA) Study is addressing three main challenges …

The ACMG offers a thorough discussion of points to consider in the clinical application of
PRS. Antegenes strongly welcomes this initiative by the eminent organization of leading …