At any point 1–5 days following ascent to altitudes≥ 2500 m, individuals are at risk of
developing one of three forms of acute altitude illness: acute mountain sickness, a syndrome …

For 200 years, the 'closed box'analogy of intracranial pressure (ICP) has underpinned
neurosurgery and neuro-critical care. Cushing conceptualised the Monro-Kellie doctrine …

High-altitude illnesses (HAIs) result from acute exposure to high altitude/hypoxia. Numerous
molecular mechanisms affect appropriate acclimatization to hypobaric and/or normobaric …

High-altitude cerebral edema (HACE) and acute mountain sickness (AMS) are
neuropathologies associated with rapid exposure to hypoxia. However, speculation remains …

Intact, coordinated, and precisely regulated cerebrovascular responses are required for the
maintenance of cerebral metabolic homeostasis, adequate perfusion, oxygen delivery, and …

After ascent to high altitude (≥ 2500 m), the inability of the human body to adapt to the
hypobaric and hypoxia environment can induce tissue hypoxia, then a series of high altitude …

BACKGROUND AND PURPOSE: Patients with idiopathic intracranial hypertension have
transverse sinus stenosis on gadolinium-bolused MRV, but other MR imaging signs are less …

Acute moderate intensity exercise has been shown to improve cognitive performance. In
contrast, hypoxia is believed to impair cognitive performance. The detrimental effects of …

Ascent to high-altitude elicits compensatory physiological adaptations in order to improve
oxygenation throughout the body. The brain is particularly vulnerable to the hypoxemia of …

Areas at high-altitude, annually attract millions of tourists, skiers, trekkers, and climbers. If not
adequately prepared and not considering certain ascent rules, a considerable proportion of …