Recent advances in Staphylococcus aureus infection: focus on vaccine development
Staphylococcus aureus normally colonizes the nasal cavity and pharynx. After breaching the
normal habitat, the organism is able to cause a number of infections at any site of the body …
normal habitat, the organism is able to cause a number of infections at any site of the body …
Understanding mechanisms of virulence in MRSA: implications for antivirulence treatment strategies
ABSTRACT Introduction Methicillin-resistant Staphylococcus aureus (MRSA) is a
widespread pathogen, often causing recurrent and deadly infections in the hospital and …
widespread pathogen, often causing recurrent and deadly infections in the hospital and …
[HTML][HTML] Staphylococcus aureus vaccine strategy: promise and challenges
U Chand, P Priyambada, PK Kushawaha - Microbiological Research, 2023 - Elsevier
Staphylococcus aureus (S. aureus) is a leading and crucial infectious threat to global public
health due to the widespread emergence of antibiotic-resistant strains such as Methicillin …
health due to the widespread emergence of antibiotic-resistant strains such as Methicillin …
[HTML][HTML] Transcutaneous immunization of recombinant Staphylococcal enterotoxin B protein using a dissolving microneedle provides potent protection against lethal …
S Liu, S Zhang, Y Duan, Y Niu, H Gu, Z Zhao, S Zhang… - Vaccine, 2019 - Elsevier
Staphylococcal enterotoxin B (SEB) produced by the Staphylococcus aureus bacteriumis
most commonly associated with food poisoning and is known to also cause toxic shock …
most commonly associated with food poisoning and is known to also cause toxic shock …
Staphylococcal enterotoxin B as DNA vaccine against breast cancer in a murine model
R Halabian, A Jahangiri, H Sedighian, E Behzadi… - International …, 2023 - Springer
Recently, many efforts have been made to treat cancer using recombinant bacterial toxins
and this strategy has been used in clinical trials of various cancers. Therapeutic DNA cancer …
and this strategy has been used in clinical trials of various cancers. Therapeutic DNA cancer …
Dietary supplementation with spray-dried animal plasma improves vaccine protection in aged mice
L Miró, C Rosell-Cardona, C Amat, J Polo… - Frontiers in …, 2023 - frontiersin.org
Background Senescence is characterized by an aggravated inflammatory state that reduces
vaccine responsiveness. Dietary supplementation with spray-dried porcine plasma (SDP) …
vaccine responsiveness. Dietary supplementation with spray-dried porcine plasma (SDP) …
SEC is an antiangiogenic virulence factor that promotes Staphylococcus aureus endocarditis independent of superantigen activity
The superantigen staphylococcal enterotoxin C (SEC) is critical for Staphylococcus aureus
infective endocarditis (SAIE) in rabbits. Superantigenicity, its hallmark function, was …
infective endocarditis (SAIE) in rabbits. Superantigenicity, its hallmark function, was …
Oral administration of recombinant Bacillus subtilis spores expressing mutant staphylococcal enterotoxin B provides potent protection against lethal enterotoxin …
Z Xiong, J Mai, F Li, B Liang, S Yao, Z Liang, C Zhang… - AMB Express, 2020 - Springer
Pathogenicity of Staphylococcus aureus is induced by staphylococcal enterotoxin B (SEB). A
mutant form of SEB (mSEB) is immunogenic as well as less toxic. Recombinant mSEB and …
mutant form of SEB (mSEB) is immunogenic as well as less toxic. Recombinant mSEB and …
[HTML][HTML] Identification of CD4+ T cell epitopes from Staphylococcus aureus secretome using immunoinformatic prediction and molecular docking
One major reason for the lack of clinical success of Staphylococcus aureus vaccine
candidates is the inability of the antigens to develop a CD4+ T cell-mediated immune …
candidates is the inability of the antigens to develop a CD4+ T cell-mediated immune …
[PDF][PDF] 金黄色葡萄球菌肠毒素B 功能表位及中和抗体研究进展
胡乃静, 罗龙龙, 乔春霞… - 中国药理学与毒理学杂志, 2020 - cjpt.magtechjournal.com
金黄色葡萄球菌(金葡菌) 肠毒素B (SEB), 是造成食物中毒乃至中毒性休克综合征的主要病因.
SEB 也是一种超级抗原, 可以刺激T 细胞, 能够同时与抗原呈递细胞上的主要组织相容性复合物 …
SEB 也是一种超级抗原, 可以刺激T 细胞, 能够同时与抗原呈递细胞上的主要组织相容性复合物 …