Lactate transport and signaling in the brain: potential therapeutic targets and roles in body—Brain interaction
LH Bergersen - Journal of Cerebral Blood Flow & …, 2015 - journals.sagepub.com
Lactate acts as a 'buffer'between glycolysis and oxidative metabolism. In addition to being
exchanged as a fuel by the monocarboxylate transporters (MCTs) between cells and tissues …
exchanged as a fuel by the monocarboxylate transporters (MCTs) between cells and tissues …
The molecular pathophysiology of concussive brain injury–an update
G Barkhoudarian, DA Hovda… - Physical Medicine and …, 2016 - pmr.theclinics.com
Concussion (mild traumatic brain injury [TBI]), particularly with organized sports, has come to
the forefront of popular culture. Affecting about 1.6 million to 3.8 million athletes a year, its …
the forefront of popular culture. Affecting about 1.6 million to 3.8 million athletes a year, its …
Hemorrhagic progression of a contusion after traumatic brain injury: a review
The magnitude of damage to cerebral tissues following head trauma is determined by the
primary injury, caused by the kinetic energy delivered at the time of impact, plus numerous …
primary injury, caused by the kinetic energy delivered at the time of impact, plus numerous …
A review of the effectiveness of neuroimaging modalities for the detection of traumatic brain injury
F Amyot, DB Arciniegas, MP Brazaitis… - Journal of …, 2015 - liebertpub.com
The incidence of traumatic brain injury (TBI) in the United States was 3.5 million cases in
2009, according to the Centers for Disease Control and Prevention. It is a contributing factor …
2009, according to the Centers for Disease Control and Prevention. It is a contributing factor …
Metabolic crisis occurs with seizures and periodic discharges after brain trauma
Objective Traumatic brain injury (TBI) results in persistent disruption of brain metabolism that
has yet to be mechanistically defined. Early post‐traumatic seizures are one potential …
has yet to be mechanistically defined. Early post‐traumatic seizures are one potential …
Cerebral extracellular chemistry and outcome following traumatic brain injury: a microdialysis study of 223 patients
I Timofeev, KLH Carpenter, J Nortje, PG Al-Rawi… - Brain, 2011 - academic.oup.com
Secondary insults can adversely influence outcome following severe traumatic brain injury.
Monitoring of cerebral extracellular chemistry with microdialysis has the potential for early …
Monitoring of cerebral extracellular chemistry with microdialysis has the potential for early …
Rapid optofluidic detection of biomarkers for traumatic brain injury via surface-enhanced Raman spectroscopy
Current technologies for the point-of-care diagnosis of traumatic brain injury (TBI) lack
sensitivity, require specialist handling or involve complicated and costly procedures. Here …
sensitivity, require specialist handling or involve complicated and costly procedures. Here …
Brain neurotrauma: molecular, neuropsychological, and rehabilitation aspects
FH Kobeissy - 2015 - books.google.com
With the contribution from more than one hundred CNS neurotrauma experts, this book
provides a comprehensive and up-to-date account on the latest developments in the area of …
provides a comprehensive and up-to-date account on the latest developments in the area of …
Impact of tight glycemic control on cerebral glucose metabolism after severe brain injury: a microdialysis study
M Oddo, JM Schmidt, E Carrera, N Badjatia… - Critical care …, 2008 - journals.lww.com
Objectives: To analyze the effect of tight glycemic control with the use of intensive insulin
therapy on cerebral glucose metabolism in patients with severe brain injury. Design …
therapy on cerebral glucose metabolism in patients with severe brain injury. Design …
Nonconvulsive electrographic seizures after traumatic brain injury result in a delayed, prolonged increase in intracranial pressure and metabolic crisis
Objective: To determine whether nonconvulsive electrographic post-traumatic seizures
result in increases in intracranial pressure and microdialysis lactate/pyruvate ratio. Design …
result in increases in intracranial pressure and microdialysis lactate/pyruvate ratio. Design …