Objective: To determine whether nonconvulsive electrographic post-traumatic seizures
result in increases in intracranial pressure and microdialysis lactate/pyruvate ratio. Design …

Traumatic brain injury (TBI) remains one of the most complex diseases known in the most
complex of all organs in the body. The causes of TBI are many and varied and include …

Traumatic brain injury (TBI) is the leading cause of death and disability in young adults.
Survivors of TBI frequently suffer from long‐term personality changes and deficits in …

Mitochondria are important for providing cellular energy ATP through the oxidative
phosphorylation pathway. They are also critical in regulating many cellular functions …

Objective: To determine if posttraumatic nonconvulsive electrographic seizures result in long-
term brain atrophy. Methods: Prospective continuous EEG (cEEG) monitoring was done in …

The complex neuropathology of traumatic brain injury (TBI) is difficult to dissect, given the
convoluted cytoarchitecture of affected brain regions such as the hippocampus …

Objectives: Hypocapnia is used in the management of acute brain injury and may be life-
saving in specific circumstances, but it can produce neuronal ischemia and injury, potentially …

Purpose: Intracerebral microdialysis (ICMD) is an accepted method for monitoring changes
in neurochemistry from acute brain injury. The goal of this pilot study was to determine the …

N-Acetylaspartate (NAA) is employed as a non-invasive marker for neuronal health using
proton magnetic resonance spectroscopy (MRS). This utility is afforded by the fact that NAA …

Oxygen monitoring has been a topic of exhaustive study given its central role in the
biochemistry of life. The ability to quantify the physiological distribution and real‐time …