Capillary transit time heterogeneity and flow-metabolism coupling after traumatic brain injury

L Østergaard, TS Engedal, R Aamand… - Journal of Cerebral …, 2014 - journals.sagepub.com
Most patients who die after traumatic brain injury (TBI) show evidence of ischemic brain
damage. Nevertheless, it has proven difficult to demonstrate cerebral ischemia in TBI …

Repetitive mild traumatic brain injury alters glymphatic clearance rates in limbic structures of adolescent female rats

J Christensen, DK Wright, GR Yamakawa, SR Shultz… - Scientific reports, 2020 - nature.com
The glymphatic system is the macroscopic waste clearance system for the central nervous
system. Glymphatic dysfunction has been linked to several neurological conditions …

Cerebral hemodynamic changes of mild traumatic brain injury at the acute stage

H Doshi, N Wiseman, J Liu, W Wang, RD Welch… - PloS one, 2015 - journals.plos.org
Mild traumatic brain injury (mTBI) is a significant public health care burden in the United
States. However, we lack a detailed understanding of the pathophysiology following mTBI …

Brain tissue oxygen-based therapy and outcome after severe traumatic brain injury: a systematic literature review

R Nangunoori, E Maloney-Wilensky, M Stiefel, S Park… - Neurocritical care, 2012 - Springer
Observational clinical studies demonstrate that brain hypoxia is associated with poor
outcome after severe traumatic brain injury (TBI). In this study, available medical literature …

Resuscitation and critical care of poor-grade subarachnoid hemorrhage

RJ Komotar, JM Schmidt, RM Starke, J Claassen… - …, 2009 - journals.lww.com
Abstract AS OUTCOMES HAVE improved for patients with aneurysmal subarachnoid
hemorrhage, most mortality and morbidity that occur today are the result of severe diffuse …

Pediatric traumatic brain injury: not just little adults

CC Giza, RB Mink, A Madikians - Current opinion in critical care, 2007 - journals.lww.com
Pediatric traumatic brain injury: not just little adults : Current Opinion in Critical Care Pediatric
traumatic brain injury: not just little adults : Current Opinion in Critical Care Log in or Register …

Comprehensive evaluation of mitochondrial redox profile, calcium dynamics, membrane integrity and apoptosis markers in a preclinical model of severe penetrating …

JD Pandya, S Musyaju, HR Modi, Y Cao… - Free Radical Biology …, 2023 - Elsevier
Abstract Traumatic Brain Injury (TBI) is caused by the external physical assaults damages
the brain. It is a heterogeneous disorder that remains a leading cause of death and disability …

Prognosis in severe brain injury

RD Stevens, R Sutter - Critical care medicine, 2013 - journals.lww.com
Background: The prediction of neurologic outcome is a fundamental concern in the
resuscitation of patients with severe brain injury. Objective: To provide an evidence-based …

Half-molar sodium lactate infusion to prevent intracranial hypertensive episodes in severe traumatic brain injured patients: a randomized controlled trial

C Ichai, JF Payen, JC Orban, H Quintard, H Roth… - Intensive care …, 2013 - Springer
Purpose Preventive treatments of traumatic intracranial hypertension are not yet established.
We aimed to compare the efficiency of half-molar sodium lactate (SL) versus saline serum …

Fasting is neuroprotective following traumatic brain injury

LM Davis, JR Pauly, RD Readnower… - Journal of …, 2008 - Wiley Online Library
To determine the neuroprotective effect of fasting after traumatic brain injury (TBI) and to
elucidate the potential underlying mechanisms, we used a controlled cortical impact (CCI) …