Brain multimodality monitoring: updated perspectives
D Roh, S Park - Current neurology and neuroscience reports, 2016 - Springer
The challenges posed by acute brain injury (ABI) involve the management of the initial insult
in addition to downstream inflammation, edema, and ischemia that can result in secondary …
in addition to downstream inflammation, edema, and ischemia that can result in secondary …
Management strategies based on multi-modality neuromonitoring in severe traumatic brain injury
C Lazaridis, B Foreman - Neurotherapeutics, 2023 - Elsevier
Secondary brain injury after neurotrauma is comprised of a host of distinct, potentially
concurrent and interacting mechanisms that may exacerbate primary brain insult …
concurrent and interacting mechanisms that may exacerbate primary brain insult …
New astroglial injury-defined biomarkers for neurotrauma assessment
J Halford, S Shen, K Itamura, J Levine… - Journal of Cerebral …, 2017 - journals.sagepub.com
Traumatic brain injury (TBI) is an expanding public health epidemic with pathophysiology
that is difficult to diagnose and thus treat. TBI biomarkers should assess patients across …
that is difficult to diagnose and thus treat. TBI biomarkers should assess patients across …
Persistent metabolic crisis as measured by elevated cerebral microdialysis lactate-pyruvate ratio predicts chronic frontal lobe brain atrophy after traumatic brain injury
Objective: To determine whether persistent metabolic dysfunction in normal-appearing
frontal lobe tissue is correlated with long-term tissue atrophy. Design: Prospective …
frontal lobe tissue is correlated with long-term tissue atrophy. Design: Prospective …
Detection of cerebral compromise with multimodality monitoring in patients with subarachnoid hemorrhage
HI Chen, MF Stiefel, M Oddo, AH Milby… - …, 2011 - journals.lww.com
BACKGROUND: Studies in traumatic brain injury suggest that monitoring techniques such
as brain tissue oxygen (Pbto 2) and cerebral microdialysis may complement conventional …
as brain tissue oxygen (Pbto 2) and cerebral microdialysis may complement conventional …
[HTML][HTML] Effects of the neurological wake-up test on clinical examination, intracranial pressure, brain metabolism and brain tissue oxygenation in severely brain-injured …
R Helbok, P Kurtz, MJ Schmidt, MR Stuart, L Fernandez… - Critical Care, 2012 - Springer
Introduction Daily interruption of sedation (IS) has been implemented in 30 to 40% of
intensive care units worldwide and may improve outcome in medical intensive care patients …
intensive care units worldwide and may improve outcome in medical intensive care patients …
[HTML][HTML] Beyond intracranial pressure: optimization of cerebral blood flow, oxygen, and substrate delivery after traumatic brain injury
P Bouzat, N Sala, JF Payen, M Oddo - Annals of intensive care, 2013 - Springer
Monitoring and management of intracranial pressure (ICP) and cerebral perfusion pressure
(CPP) is a standard of care after traumatic brain injury (TBI). However, the pathophysiology …
(CPP) is a standard of care after traumatic brain injury (TBI). However, the pathophysiology …
Effect of hyperoxia on regional oxygenation and metabolism after severe traumatic brain injury: preliminary findings
Objective: To determine the effect of normobaric hyperoxia on cerebral metabolism in
patients with severe traumatic brain injury. Design: Prospective clinical investigation. Setting …
patients with severe traumatic brain injury. Design: Prospective clinical investigation. Setting …
Early cerebral metabolic crisis after TBI influences outcome despite adequate hemodynamic resuscitation
Background Optimal resuscitation after traumatic brain injury (TBI) remains uncertain. We
hypothesize that cerebral metabolic crisis is frequent despite adequate resuscitation of the …
hypothesize that cerebral metabolic crisis is frequent despite adequate resuscitation of the …
Imaging after brain injury
JP Coles - British journal of anaesthesia, 2007 - academic.oup.com
Head injury remains an important cause of death and disability in young adults. This review
will discuss the role of structural imaging using computed tomography (CT) and magnetic …
will discuss the role of structural imaging using computed tomography (CT) and magnetic …