Mitochondrial failure has long been associated with programmed axon death (Wallerian
degeneration, WD), a widespread and potentially preventable mechanism of axon …

There has recently been a resurgence of interest in psychedelic compounds based on
studies demonstrating their potential therapeutic applications in treating post-traumatic …

Overproduction of reactive oxygen species (ROS) and cumulative oxidative stress induce
the degeneration of neuromelanin-containing dopaminergic neurons in the substantia nigra …

Chronic neuroinflammation is implicated in the pathogenesis of Parkinson's disease (PD),
one of the most common neurodegenerative diseases. Itaconate, an endogenous metabolite …

Sex hormones and genes on the sex chromosomes are not only key factors in the regulation
of sexual differentiation and reproduction but they are also deeply involved in brain …

Neurodegenerative disorders such as Parkinson's (PD) and Huntington's disease (HD) are
characterized by a selective detrimental impact on neurons in a specific brain area …

Neurological disorders affect billions of people across the world, making the discovery of
effective treatments an important challenge. The evaluation of drug efficacy is further …

Parkinson's disease (PD) is a progressive neurodegenerative disorder, whose treatment
with modern therapeutics leads to a plethora of side effects with prolonged usage …

Parkinson's disease (PD) is the second most common neurodegenerative disease and
primarily characterized by the loss of dopaminergic neurons in the substantia nigra pars …

Neuronal disorders are characterized by the loss of functional neurons and disrupted
neuroanatomical connectivity, severely impacting the quality of life of patients. This study …