Chronic myeloid leukemia provides an illustrative disease model for both molecular
pathogenesis of cancer and rational drug therapy. Chronic myeloid leukemia is a clonal …

Disseminating disease is a predictive and prognostic indicator of poor outcome in children
with neuroblastoma. Its accurate and sensitive assessment can facilitate optimal treatment …

BACKGROUND AND OBJECTIVES: To maximize graft-versus-leukemia (GVL) effects while
minimizing the risk of graft-versus-host disease (GVHD), we undertook a study of allogeneic …

Abstract Analysis of changes in recipient and donor hemopoietic cell origin is extremely
useful to monitor the effect of stem cell transplantation (SCT) and sequential adoptive …

Donor lymphocyte infusions (DLI) have been the mainstay of treatment for chronic myeloid
leukemia (CML) relapsing after allogeneic stem cell transplantation (allo-SCT). Imatinib …

The monitoring of minimal residual disease (MRD) through low sensitivity real-time (RT)
polymerase chain reaction (PCR) analysis of BCR-ABL transcripts allows early detection of …

The aim of the study was to evaluate if thymidine kinase (TK) correlated with duration of first
remission (DFR) or survival in dogs with lymphoma and if initial TK levels correlated with …

We demonstrate sorting of rare cancer cells from blood using a thin ribbon monolayer of
cells within a credit-card sized, microfluidic laboratory-on-a-card (“lab card”) structure. This …

GVHD is a life-threatening complication of allogeneic hematopoietic stem cell
transplantation (HSCT). GVHD is due to donor lymphocytes that are cotransplanted with …

Chronic myeloid leukaemia (CML) is a clonal disorder of the pluripotent haematopoietic
stem cell. The typical triphasic course of CML starts with the premalignant chronic phase …