Medical case reports suggest that cannabinoids extracted from Cannabis sativa have
therapeutic effects; however, the therapeutic employment is limited due to the psychotropic …

The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a
balance in internal environment (temperature, mood, and immune system) and energy input …

In the last decades, a lot of attention has been paid to the compounds present in medicinal
Cannabis sativa L., such as Δ9‐tetrahydrocannabinol (Δ9‐THC) and cannabidiol (CBD) …

Endogenous bioactive lipids are part of a complex network that modulates a plethora of
cellular and molecular processes involved in health and disease, of which inflammation …

The gut microbiome is considered an organ contributing to the regulation of host
metabolism. Since the relationship between the gut microbiome and specific diseases was …

Various studies aiming to elucidate the role of the gut microbiome-metabolome co-axis in
health and disease have primarily focused on water-soluble polar metabolites, whilst non …

Inflammatory bowel disease (IBD) is a general term used to describe a group of chronic
inflammatory conditions of the gastrointestinal tract of unknown etiology, including two …

As perspectives on cannabis continue to shift, understanding the physiological and
behavioral effects of cannabis use is of paramount importance. Previous data suggest that …

The management of visceral pain in patients with disorders of gut–brain interaction, notably
irritable bowel syndrome, presents a considerable clinical challenge, with few available …

Background: Various neurocognitive and mental health-related conditions have been
associated with the gut microbiome, implicating a microbiome–gut–brain axis (MGBA). The …