Pharmaceutical cocrystals represent a distinctive class of crystal engineered
multicomponent systems consisting an API and a crystal former non-covalently linked …

One of the most popular strategies of the optimization of drug properties in the
pharmaceutical industry appears to be a solid form changing into a cocrystalline form. A …

On the basis of literature analysis, we have built a database containing fusion temperatures
of two-component molecular cocrystals and individual compounds (1947 cocrystals/salts). In …

Through cocrystallization of the broad-spectrum antifungal agent fluconazole (FLZ) with a
number of nutraceuticals, we have isolated three distinct solid forms of the drug, namely …

Affinity prediction computations based on the COSMO-RS approach of the active
pharmaceutical ingredient (API) carbamazepine has been performed with 75 coformers. A …

Co-crystallizations can be utilized for generating new solid forms of a target substance in
order to alter or enhance some specific bulk physical property. Generally, selection of the co …

The influence of temperature and solvent on the solid–liquid phase diagram of the 1: 1
sulfamethazine–salicylic acid co-crystal has been investigated. Ternary phase diagrams of …

This work demonstrates how the thermodynamics of cocrystal formation from the pure, solid
coformers can be directly determined from experimentally obtained calorimetric data, without …

In this work, three new cocrystals of the nonsteroidal anti-inflammatory drug flurbiprofen with
salicylamide, benzamide, and picolinamide have been discovered using thermodynamic …

Based on literature analysis, we have built a database containing fusion temperatures and
enthalpies of two-component molecular co-crystals and individual compounds (2170 co …