[HTML][HTML] The molecular activity of cannabidiol in the regulation of Nrf2 system interacting with NF-κB pathway under oxidative stress

SA Ekiner, A Gęgotek, E Skrzydlewska - Redox Biology, 2022 - Elsevier
Cannabidiol (CBD), the major non-psychoactive phytocannabinoid of Cannabis sativa L., is
one of the most studied compounds in pharmacotherapeutic approaches to treat oxidative …

[HTML][HTML] Understanding and overcoming immunosuppression shaped by cancer stem cells

L Li, RA Jensen - Cancer Research, 2023 - AACR
Use of immunotherapy in recent years has revolutionized cancer treatment for certain types
of cancers. However, the broad utility of immunotherapy is limited because there are still …

[HTML][HTML] Anticancer potential of sulfonamide moieties via in-vitro and in-silico approaches: comparative investigations for future drug development

TA Wani, S Zargar, HM Alkahtani, N Altwaijry… - International Journal of …, 2023 - mdpi.com
Several kinds of anticancer drugs are presently commercially accessible, but low efficacy,
solubility, and toxicity have reduced the overall therapeutic indices. Thus, the search for …

[HTML][HTML] MicroRNAs: important players in breast cancer angiogenesis and therapeutic targets

BM Hussen, ST Abdullah, MF Rasul, A Salihi… - Frontiers in molecular …, 2021 - frontiersin.org
The high incidence of breast cancer (BC) is linked to metastasis, facilitated by tumor
angiogenesis. MicroRNAs (miRNAs or miRs) are small non-coding RNA molecules that …

[HTML][HTML] Functional interplay between long non-coding RNAs and Breast CSCs

BM Hussen, RK Kheder, ST Abdullah, HJ Hidayat… - Cancer Cell …, 2022 - Springer
Breast cancer (BC) represents aggressive cancer affecting most women's lives globally.
Metastasis and recurrence are the two most common factors in a breast cancer patient's …

Signaling pathways modulated by miRNAs in breast cancer angiogenesis and new therapeutics

BM Hussen, A Salihi, ST Abdullah, MF Rasul… - … -Research and Practice, 2022 - Elsevier
MicroRNAs (miRNAs) act as oncogenes or tumor suppressors by suppressing the
expression of target genes, some of which are engaged in angiogenic signaling pathways …

[HTML][HTML] Sepsis-mediated renal dysfunction: Pathophysiology, biomarkers and role of phytoconstituents in its management

A Balkrishna, S Sinha, A Kumar, V Arya… - Biomedicine & …, 2023 - Elsevier
Sepsis has evolved as an enormous health issue amongst critically ill patients. It is a major
risk factor that results in multiple organ failure and shock. Acute kidney injury (AKI) is one of …

Multiple function of lncRNA MALAT1 in cancer occurrence and progression

F Malakoti, N Targhazeh, H Karimzadeh… - Chemical biology & …, 2023 - Wiley Online Library
Long non‐coding RNAs (lncRNAs) have received particular attention in the last decade due
to its engaging in carcinogenesis and tumorigenesis. Metastasis‐associated lung …

Noncoding RNAs improve the predictive power of network medicine

D Morselli Gysi, AL Barabási - Proceedings of the National …, 2023 - National Acad Sciences
Network medicine has improved the mechanistic understanding of disease, offering
quantitative insights into disease mechanisms, comorbidities, and novel diagnostic tools and …

A review of non-coding RNA related to NF-κB signaling pathway in the pathogenesis of osteoarthritis

T Feng, Q Wu - International Immunopharmacology, 2022 - Elsevier
Osteoarthritis (OA), often called as “wear and tear” arthritis, is the most common form of
degenerative joint arthritis and is a leading cause of disability. The nuclear factor-kappaB …