[HTML][HTML] The molecular activity of cannabidiol in the regulation of Nrf2 system interacting with NF-κB pathway under oxidative stress
SA Ekiner, A Gęgotek, E Skrzydlewska - Redox Biology, 2022 - Elsevier
Cannabidiol (CBD), the major non-psychoactive phytocannabinoid of Cannabis sativa L., is
one of the most studied compounds in pharmacotherapeutic approaches to treat oxidative …
one of the most studied compounds in pharmacotherapeutic approaches to treat oxidative …
[HTML][HTML] Understanding and overcoming immunosuppression shaped by cancer stem cells
L Li, RA Jensen - Cancer Research, 2023 - AACR
Use of immunotherapy in recent years has revolutionized cancer treatment for certain types
of cancers. However, the broad utility of immunotherapy is limited because there are still …
of cancers. However, the broad utility of immunotherapy is limited because there are still …
[HTML][HTML] Anticancer potential of sulfonamide moieties via in-vitro and in-silico approaches: comparative investigations for future drug development
Several kinds of anticancer drugs are presently commercially accessible, but low efficacy,
solubility, and toxicity have reduced the overall therapeutic indices. Thus, the search for …
solubility, and toxicity have reduced the overall therapeutic indices. Thus, the search for …
[HTML][HTML] MicroRNAs: important players in breast cancer angiogenesis and therapeutic targets
The high incidence of breast cancer (BC) is linked to metastasis, facilitated by tumor
angiogenesis. MicroRNAs (miRNAs or miRs) are small non-coding RNA molecules that …
angiogenesis. MicroRNAs (miRNAs or miRs) are small non-coding RNA molecules that …
[HTML][HTML] Functional interplay between long non-coding RNAs and Breast CSCs
Breast cancer (BC) represents aggressive cancer affecting most women's lives globally.
Metastasis and recurrence are the two most common factors in a breast cancer patient's …
Metastasis and recurrence are the two most common factors in a breast cancer patient's …
Signaling pathways modulated by miRNAs in breast cancer angiogenesis and new therapeutics
MicroRNAs (miRNAs) act as oncogenes or tumor suppressors by suppressing the
expression of target genes, some of which are engaged in angiogenic signaling pathways …
expression of target genes, some of which are engaged in angiogenic signaling pathways …
[HTML][HTML] Sepsis-mediated renal dysfunction: Pathophysiology, biomarkers and role of phytoconstituents in its management
Sepsis has evolved as an enormous health issue amongst critically ill patients. It is a major
risk factor that results in multiple organ failure and shock. Acute kidney injury (AKI) is one of …
risk factor that results in multiple organ failure and shock. Acute kidney injury (AKI) is one of …
Multiple function of lncRNA MALAT1 in cancer occurrence and progression
F Malakoti, N Targhazeh, H Karimzadeh… - Chemical biology & …, 2023 - Wiley Online Library
Long non‐coding RNAs (lncRNAs) have received particular attention in the last decade due
to its engaging in carcinogenesis and tumorigenesis. Metastasis‐associated lung …
to its engaging in carcinogenesis and tumorigenesis. Metastasis‐associated lung …
Noncoding RNAs improve the predictive power of network medicine
D Morselli Gysi, AL Barabási - Proceedings of the National …, 2023 - National Acad Sciences
Network medicine has improved the mechanistic understanding of disease, offering
quantitative insights into disease mechanisms, comorbidities, and novel diagnostic tools and …
quantitative insights into disease mechanisms, comorbidities, and novel diagnostic tools and …
A review of non-coding RNA related to NF-κB signaling pathway in the pathogenesis of osteoarthritis
T Feng, Q Wu - International Immunopharmacology, 2022 - Elsevier
Osteoarthritis (OA), often called as “wear and tear” arthritis, is the most common form of
degenerative joint arthritis and is a leading cause of disability. The nuclear factor-kappaB …
degenerative joint arthritis and is a leading cause of disability. The nuclear factor-kappaB …