Recent strategies and advances in the fabrication of nano lipid carriers and their application towards brain targeting
In last two decades, the lipid nanocarriers have been extensively investigated for their drug
targeting efficiency towards the critical areas of the human body like CNS, cardiac region …
targeting efficiency towards the critical areas of the human body like CNS, cardiac region …
[HTML][HTML] The application of multifunctional nanomaterials in Alzheimer's disease: A potential theranostics strategy
Y Xu, M Zhao, D Zhou, T Zheng, H Zhang - Biomedicine & …, 2021 - Elsevier
By virtue of their small size, nanomaterials can cross the blood-brain barrier and, when
modified to target specific cells or regions, can achieve high bioavailability at the intended …
modified to target specific cells or regions, can achieve high bioavailability at the intended …
Nanotargeting of drug (s) for delaying dementia: relevance of covid-19 impact on dementia
JS D'Arrigo - American Journal of Alzheimer's Disease & …, 2020 - journals.sagepub.com
By incorporating appropriate drug (s) into lipid (biobased) nanocarriers, one obtains a
combination therapeutic for dementia treatment that targets certain cell-surface scavenger …
combination therapeutic for dementia treatment that targets certain cell-surface scavenger …
[HTML][HTML] Biomimetic nanocarrier targeting drug (s) to upstream-receptor mechanisms in dementia: focusing on linking pathogenic cascades
JS D'Arrigo - Biomimetics, 2020 - mdpi.com
Past published studies have already documented that, subsequent to the intravenous
injection of colloidal lipid nanocarriers, apolipoprotein (apo) AI is adsorbed from the blood …
injection of colloidal lipid nanocarriers, apolipoprotein (apo) AI is adsorbed from the blood …
[HTML][HTML] Alzheimer's disease, brain injury, and CNS nanotherapy in humans: Sonoporation augmenting drug targeting
JS D'Arrigo - Medical Sciences, 2017 - mdpi.com
Owing to the complexity of neurodegenerative diseases, multiple cellular types need to be
targeted simultaneously in order for a given therapy to demonstrate any major effectiveness …
targeted simultaneously in order for a given therapy to demonstrate any major effectiveness …
[HTML][HTML] Arterial elasticity: Linking of cardiovascular risks, pulse pressure, dementia, aging, and drug targeting
J D'Arrigo - OBM Neurobiology, 2022 - lidsen.com
Cerebrovascular atherosclerosis, and several other cardiovascular (or" inflamm-aging" type)
diseases, are more frequent and advanced in subjects with Alzheimer's disease compared …
diseases, are more frequent and advanced in subjects with Alzheimer's disease compared …
[HTML][HTML] Targeting Early Dementia: Using Lipid Cubic Phase Nanocarriers to Cross the Blood–Brain Barrier
JS D'Arrigo - Biomimetics, 2018 - mdpi.com
Over the past decades, a frequent co-morbidity of cerebrovascular pathology and
Alzheimer's disease has been observed. Numerous published studies indicate that the …
Alzheimer's disease has been observed. Numerous published studies indicate that the …
Microbubble based sonoporation—from the basics into clinical implications
Sonoporation is a rapidly developing novel technique serving for drug delivery and non-viral
gene therapy. It is based on the interaction between microbubbles located in the …
gene therapy. It is based on the interaction between microbubbles located in the …
[HTML][HTML] Pathophysiological linkage between aging and cognitive decline: implications for dementia treatment
J D'Arrigo - OBM Integrative and Complementary Medicine, 2022 - lidsen.com
The cardiovascular risk factors for dementia trigger widespread inflammation and oxidative
stress. These two interacting processes lead to neurodegeneration, gradual …
stress. These two interacting processes lead to neurodegeneration, gradual …
Network Pharmacology and molecular docking approach to unveil the mechanism of Hypericum perforatum in the management of Alzheimer's disorder
V Dogra, M Choudhary, A Parashar, N Choudhary - bioRxiv, 2023 - biorxiv.org
The pathogenesis of Alzheimer's disease (AD) is not fully understood which limits the
availability of safer and more efficient therapeutic strategies for the management of AD …
availability of safer and more efficient therapeutic strategies for the management of AD …