Mechanobiology: A landscape for reinterpreting stem cell heterogeneity and regenerative potential in diseased tissues

R Tassinari, E Olivi, C Cavallini, V Taglioli, C Zannini… - iScience, 2023 - cell.com
Mechanical forces play a fundamental role in cellular dynamics from the molecular level to
the establishment of complex heterogeneity in somatic and stem cells. Here, we highlight the …

Cytochalasins as Modulators of Stem Cell Differentiation

L Pampanella, G Petrocelli, PM Abruzzo, C Zucchini… - Cells, 2024 - mdpi.com
Regenerative medicine aims to identify new research strategies for the repair and
restoration of tissues damaged by pathological or accidental events. Mesenchymal stem …

Azithromycin-loaded liposomes and niosomes for the treatment of skin infections: Influence of excipients and preparative methods on the functional properties

A Abruzzo, R Pucci, PM Abruzzo, S Canaider… - European Journal of …, 2024 - Elsevier
The aim of this study was to develop azithromycin (AZT)-loaded liposomes (LP) and
niosomes (NS) useful for the treatment of bacterial skin infections and acne. LP based on …

Six Unprecedented Cytochalasin Derivatives from the Potato Endophytic Fungus Xylaria curta E10 and Their Cytotoxicity

X Zhang, Y Fan, K Ye, X Pan, X Ma, H Ai, B Shi, J Liu - Pharmaceuticals, 2023 - mdpi.com
Six previously undescribed cytochalasins, Curtachalasins X1–X6 (1–6), together with six
known compounds (7–12) were isolated from the endophytic fungus Xylaria curta E10 …

Oxytocin Modulates Osteogenic Commitment in Human Adipose-Derived Stem Cells

G Petrocelli, PM Abruzzo, L Pampanella… - International Journal of …, 2023 - mdpi.com
Human adipose-derived stem cells (hASCs) are commonly harvested in minimally invasive
contexts with few ethical concerns, and exhibit self-renewal, multi-lineage differentiation …

Cytochalasin B influences cytoskeletal organization and osteogenic potential of human Wharton's jelly mesenchymal stem cells

L Pampanella, PM Abruzzo, R Tassinari… - Pharmaceuticals, 2023 - mdpi.com
Among perinatal stem cells of the umbilical cord, human Wharton's jelly mesenchymal stem
cells (hWJ-MSCs) are of great interest for cell-based therapy approaches in regenerative …

Synergistic Responses of Tibetan Sheep Rumen Microbiota, Metabolites, and the Host to the Plateau Environment

Y Sha, X Guo, Y He, W Li, X Liu, S Zhao, J Hu… - International Journal of …, 2023 - mdpi.com
Plateau adaptation in animals involves genetic mechanisms as well as coevolutionary
mechanisms of the microbiota and metabolome of the animal. Therefore, the characteristics …

EVL Promotes Osteo‐/Odontogenic Differentiation of Dental Pulp Stem Cells via Activating JNK Signaling Pathway

K Zeng, Q Kang, Y Li, W Li, Q Cheng… - Stem Cells …, 2023 - Wiley Online Library
Objective. Human dental pulp stem cells (hDPSCs) were recognized as a suitable and
promising source of stem cells in dental pulp regeneration. However, the mechanism by …

TRPML1 ion channel promote HepaRG cells differentiation under simulated microgravity conditions

M Gao, H Fan, D Lü, Z Lu, H Li, Z Qi, S Sun, D Guan… - 2023 - researchsquare.com
Stem cell differentiation must be regulated by intricate and complex interactions between
cells and their surrounding environment, ensuring normal organ and tissue morphology …

[PDF][PDF] Research Article EVL Promotes Osteo-/Odontogenic Differentiation of Dental Pulp Stem Cells via Activating JNK Signaling Pathway

K Zeng, Q Kang, Y Li, W Li, Q Cheng, W Xia - 2023 - scienceopen.com
Objective. Human dental pulp stem cells (hDPSCs) were recognized as a suitable and
promising source of stem cells in dental pulp regeneration. However, the mechanism by …