Bromodomain and extraterminal domain (BET) proteins, which are important epigenetic
readers, are often dysregulated in cancer. While a number of BET inhibitors are currently in …

Melissa officinalis (MO) is a medicinal plant well-known for its multiple pharmacological
effects, including anti-inflammatory, anticancer and beneficial effects on skin recovery. In this …

Introduction Cannabidiol (CBD), a phytocannabinoid from Cannabis sativa, has several
therapeutic properties. However, its high lipophilicity, metabolization, and instability impair …

Background Cisplatin (CDDP) is commonly used to treat non-small cell lung cancer
(NSCLC), but the appearance of drug resistance greatly hinders its efficacy. Borneol may …

The Notch signaling pathway is an evolutionarily conserved pathway that modulates normal
biological processes involved in cellular differentiation, apoptosis, and stem cell self …

Initially described as an ancient and highly conserved catabolic biofunction, autophagy
plays a significant role in disease pathogenesis and progression. As the bioactive ingredient …

Introduction Super-paramagnetic iron oxide nanoparticles (SPIONs) are known as promising
theranostic nano-drug carriers with magnetic resonance imaging (MRI) properties. Applying …

Many countries are endeavoring to strengthen the competitiveness of their biological
resources by exploring and developing wild endemic plants. This study examined the effects …

The QSAR models are employed to predict the anti-proliferative activity of 81 derivatives of
flavonol against prostate cancer using the Monte Carlo algorithm based on the index of …

For a long time, hydrogen sulfide (H2S) has been considered a toxic compound, but recent
studies have found that H2S is the third gaseous signaling molecule which plays a vital role …