Synthesis, characterization, and evaluation of in vitro cytotoxicity and in vivo antitumor activity of asiatic acid-loaded poly lactic-co-glycolic acid nanoparticles: A …

S Dutta, P Chakraborty, S Basak, S Ghosh, N Ghosh… - Life Sciences, 2022 - Elsevier
Asiatic acid (AA), an aglycone of pentacyclic triterpene glycoside, obtained from the leaves
of Centella asiatica exerts anticancer effects by inhibiting cellular proliferation and inducing …

A network pharmacology approach to investigate the anticancer mechanism of cinobufagin against hepatocellular carcinoma via downregulation of EGFR-CDK2 …

A Yang, Q Wu, Z Hu, S Wang, Y Tao, A Wang… - Toxicology and applied …, 2021 - Elsevier
Hepatocellular carcinoma (HCC) is one of the deadliest cancers with high mortality and poor
prognosis, and the investigation on new approaches and effective drugs for HCC therapy is …

Narciclasine induces autophagy-mediated apoptosis in gastric cancer cells through the Akt/mTOR signaling pathway

Y Yuan, X He, X Li, Y Liu, Y Tang, H Deng… - BMC Pharmacology and …, 2021 - Springer
Background Gastric cancer is a common gastrointestinal cancer and currently has the third-
highest mortality rate. Research shows that the natural compound narciclasine has a variety …

[HTML][HTML] Cancer treatment: Role of natural products. Time to have a serious rethink

SB Mali - Oral Oncology Reports, 2023 - Elsevier
Natural products are chemical compounds or substances produced naturally by living
organisms. With the development of modern technology, natural products have become …

Liensinine, a Novel and Food-Derived Compound, Exerts Potent Antihepatoma Efficacy via Inhibiting the Kv10. 1 Channel

B Ma, S Shi, W Guo, H Zhang, Z Zhao… - Journal of Agricultural …, 2024 - ACS Publications
Plant metabolites from natural product extracts offer unique advantages against
carcinogenesis in the development of drugs. The target-based virtual screening from food …

An overview of natural products that modulate the expression of non-coding RNAs involved in oxidative stress and inflammation-associated disorders

JA Ngum, FJ Tatang, MH Toumeni… - Frontiers in …, 2023 - frontiersin.org
Oxidative stress is a state in which oxidants are produced in excess in the body's tissues and
cells, resulting in a biological imbalance amid the generation of reactive oxygen and …

The impact of light wavelength and darkness on metabolite profiling of Korean Ginseng: evaluating its anti-cancer potential against MCF-7 and BV-2 cell lines

NB Sadiq, H Kwon, NI Park, M Hamayun… - International Journal of …, 2023 - mdpi.com
Korean ginseng is a source of functional foods and medicines; however, its productivity is
hindered by abiotic stress factors, such as light. This study investigated the impacts of …

Citrinin as a potential anti-cancer therapy: a comprehensive review

AAPM de Menezes, RPS Aguiar, JVO Santos… - Chemico-Biological …, 2023 - Elsevier
Citrinin (CIT) is a polyketide-derived mycotoxin, which is produced by many fungal strains
belonging to the gerena Monascus, Aspergillus, and Penicillium. It has been postulated that …

Insights of ethyl acetate fraction from Vassobia breviflora in multidrug-resistant bacteria and cancer cells: from biological to therapeutic

A Rossato Viana, N Bianchin Bottari… - Journal of Toxicology …, 2022 - Taylor & Francis
Cancer and infectious diseases are among the leading causes of death in the world. Despite
the diverse array of treatments available, challenges posed by resistance, side effects, high …

Novel nanomicelles based on rebaudioside A: a potential nanoplatform for oral delivery of honokiol with enhanced oral bioavailability and antitumor activity

J Wang, H Yang, Q Li, X Wu, G Di, J Fan, D Wei… - International journal of …, 2020 - Elsevier
Honokiol (HK) has a variety of biological activities, but its poor solubility limits its application.
Rebaudioside A (RA) is able to self-assemble into micelles, which can be used for oral …