Sinensetin isolated from Orthosiphon aristatus inhibits cell proliferation and induces apoptosis in hepatocellular carcinoma cells

D Samidurai, AK Pandurangan, SK Krishnamoorthi… - Process …, 2020 - Elsevier
Orthosiphon aristatus is a traditional folk medicine extensively used in Southeast Asia
because of its various pharmacological effects, including antioxidant, antitumor, and …

High-throughput screening identifies stevioside as a potent agent to induce apoptosis in bladder cancer cells

C Chen, X Na, L Wang, R Yu - Biochemical pharmacology, 2022 - Elsevier
Background Bladder cancer (BC) is a global health issue that lacks effective treatment
strategies. Growing evidence suggests that various natural products possess anti-tumour …

BCL2L1 is identified as a target of naringenin in regulating ovarian cancer progression

J Xu, Z Guo, S Yuan, H Li - Molecular and Cellular Biochemistry, 2022 - Springer
Naringenin is a natural bioactive flavonoid with a wide spectrum of biological activities,
including anti-carcinogenic ability. Our study aimed to investigate the effect of naringenin on …

Synthesis and cytotoxic activity of novel betulin derivatives containing hydrazide-hydrazone moieties

J Wu, J Wang, Y Han, Y Lin… - Natural Product …, 2021 - journals.sagepub.com
A series of novel betulin derivatives containing hydrazide-hydrazone moieties were
synthesized. All compounds were evaluated for their cytotoxicity against four human …

Lentinan induces apoptosis of mouse hepatocellular carcinoma cells through the EGR1/PTEN/AKT signaling axis

J You, Q Wu, Y Li, X Li, Z Lin, J Huang… - Oncology …, 2023 - spandidos-publications.com
Lentinan (LNT) isolated from Lentinus edodes is a vital host defense potentiator previously
utilized as an adjuvant in cancer therapy. The present study investigated the effect of LNT on …

Magnetic resonance imaging assessment of body composition parameters in Crohn's disease

G Labarthe, M Dolores, M Verdalle-Cazes… - Digestive and Liver …, 2020 - Elsevier
Background Body composition, currently evaluated by computed tomography scan, is
related to poor evolution and severity of Crohn's disease (CD). Few MRI studies have been …

[HTML][HTML] Hibiscus syriacus L. cultivated in callus culture exerts cytotoxicity in colorectal cancer via Notch signaling-mediated cholesterol biosynthesis suppression

XY Xu, HS Choi, SY Park, JK Kim, KH Seo, H Kim… - Phytomedicine, 2022 - Elsevier
Background In our previous study, Hibiscus syriacus leaf tissue was successfully cultivated
in an optimized callus culture system, and subsequently extracted with 70% ethanol to …

[PDF][PDF] Notch Signaling Suppression by Golden Phytochemicals: Potential for Cancer Therapy

MK Zenjanab, N Hashemzadeh… - Advanced …, 2024 - pdfs.semanticscholar.org
Cancer is one of the main causes of mortality worldwide. Cancer cells are characterized by
unregulated cellular processes, including proliferation, progression, and angiogenesis. The …

[HTML][HTML] Identification, evaluation the source of natural bioactive compounds from Calotropis gigantea l. flowers and their anticancer potential

S Devanesan, MS AlSalhi - Journal of King Saud University-Science, 2024 - Elsevier
Background In the intensified search to derive biologically active compounds from natural
products for various health care issues, attention is focused on non-edible plant sources …

Chalcone derivatives and their activities against drug-resistant cancers: an overview

J Xiao, M Gao, Q Diao, F Gao - Current Topics in Medicinal …, 2021 - ingentaconnect.com
Drug resistance, including multidrug resistance resulting from different defensive
mechanisms in cancer cells, is the leading cause of the failure of the cancer therapy, posing …