Metastasis formation is the major cause of death in most patients with cancer. Despite
extensive research, targeting metastatic seeding and colonization is still an unresolved …

With the advent of effective tools to study lipids, including mass spectrometry-based
lipidomics, lipids are emerging as central players in cancer biology. Lipids function as …

Many epithelial tumors grow in the vicinity of or metastasize to adipose tissue. As tumors
develop, crosstalk between adipose tissue and cancer cells leads to changes in adipocyte …

Cancer remains the second leading cause of mortality worldwide. In the course of this
multistage and multifactorial disease, a set of alterations takes place, with genetic and …

Growing evidence has highlighted the immune response as an important feature of
carcinogenesis and therapeutic efficacy in clear cell renal cell carcinoma (ccRCC). This …

Acetyl-CoA, as an important molecule, not only participates in multiple intracellular
metabolic reactions, but also affects the post-translational modification of proteins, playing a …

Lipid metabolism reprograming, as a hallmark of malignancy, has received renewed interest
in recent years in such areas as energy sources, cell membrane components, and signaling …

Hepatocellular carcinoma (HCC) is a primary malignancy of the liver with a high worldwide
prevalence and poor prognosis. Researches are urgently needed on its molecular …

Long interspersed nuclear element-1 (LINE-1) retrotransposition is a major hallmark of
cancer accompanied by global chromosomal instability, genomic instability, and genetic …

Fusobacterium nucleatum is a critical microbe that contributes to colorectal cancer
progression and chemoresistance. However, whether and how F. nucleatum regulates …