[HTML][HTML] Metabolic syndrome, aging and involvement of oxidative stress
F Bonomini, LF Rodella, R Rezzani - Aging and disease, 2015 - ncbi.nlm.nih.gov
The prevalence of the metabolic syndrome, a cluster of cardiovascular risk factors
associated with obesity and insulin resistance, is dramatically increasing in Western and …
associated with obesity and insulin resistance, is dramatically increasing in Western and …
[HTML][HTML] Resistin: A reappraisal
E Acquarone, F Monacelli, R Borghi, A Nencioni… - Mechanisms of ageing …, 2019 - Elsevier
From a biological point of view, aging can be considered a progressive inability of an
organism to react to stress, maintain homeostasis, and survive unfavourable changes during …
organism to react to stress, maintain homeostasis, and survive unfavourable changes during …
[PDF][PDF] Low-grade systemic inflammation connects aging, metabolic syndrome and cardiovascular disease
V Guarner, ME Rubio-Ruiz - Aging and health-a systems biology …, 2015 - library.oapen.org
Aging is associated with immunosenescence and accompanied by a chronic inflammatory
state which contributes to metabolic syndrome, diabetes and their cardiovascular …
state which contributes to metabolic syndrome, diabetes and their cardiovascular …
[HTML][HTML] Role of IGF-1 system in the modulation of longevity: controversies and new insights from a centenarians' perspective
G Vitale, G Pellegrino, M Vollery… - Frontiers in …, 2019 - frontiersin.org
Human aging is currently defined as a physiological decline of biological functions in the
body with a continual adaptation to internal and external damaging. The endocrine system …
body with a continual adaptation to internal and external damaging. The endocrine system …
[HTML][HTML] Subclass-specific IgG glycosylation is associated with markers of inflammation and metabolic health
This study indicates that glycosylation of immunoglobulin G, the most abundant antibody in
human blood, may convey useful information with regard to inflammation and metabolic …
human blood, may convey useful information with regard to inflammation and metabolic …
Genome‐wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited
By studying the loci that contribute to human longevity, we aim to identify mechanisms that
contribute to healthy aging. To identify such loci, we performed a genome‐wide association …
contribute to healthy aging. To identify such loci, we performed a genome‐wide association …
Lipidomics of familial longevity
Middle‐aged offspring of nonagenarians, as compared to their spouses (controls), show a
favorable lipid metabolism marked by larger LDL particle size in men and lower total …
favorable lipid metabolism marked by larger LDL particle size in men and lower total …
Osteosarcopenic obesity syndrome: what is it and how can it be identified and diagnosed?
Conditions related to body composition and aging, such as osteopenic obesity,
sarcopenia/sarcopenic obesity, and the newly termed osteosarcopenic obesity (triad of bone …
sarcopenia/sarcopenic obesity, and the newly termed osteosarcopenic obesity (triad of bone …
[HTML][HTML] Insulin, aging, and the brain: mechanisms and implications
AA Akintola, D van Heemst - Frontiers in endocrinology, 2015 - frontiersin.org
There is now an impressive body of literature implicating insulin and insulin signaling in
successful aging and longevity. New information from in vivo and in vitro studies concerning …
successful aging and longevity. New information from in vivo and in vitro studies concerning …
Gene expression analysis of mTOR pathway: association with human longevity
Summary mTOR signalling is implicated in the development of disease and in lifespan
extension in model organisms. This pathway has been associated with human diseases …
extension in model organisms. This pathway has been associated with human diseases …