Screening, genetic variants, and bipolar disorders: can useful hypotheses arise from the sum of partial failures?

MG Carta, G Kalcev, A Scano, S Pinna… - Clinics and …, 2023 - mdpi.com
Bipolar disorder (BD) is a relevant public health issue, therefore accurate screening tools
could be useful. The objective of this study is to verify the accuracy of the Mood Disorder …

[HTML][HTML] MIR137 polygenic risk for schizophrenia and ephrin-regulated pathway: Role in lateral ventricles and corpus callosum volume

GAM Blokland, N Maleki, J Jovicich… - International Journal of …, 2024 - Elsevier
Abstract Background/Objective. Enlarged lateral ventricle (LV) volume and decreased
volume in the corpus callosum (CC) are hallmarks of schizophrenia (SZ). We previously …

Effects of CACNA1C and ANK3 on cognitive function in patients with bipolar disorder

Y Yang, Z Zhu, L Hui, P Sun - Progress in Neuro-Psychopharmacology and …, 2024 - Elsevier
Bipolar disorder (BD) is a complex, severe mental illness with cognitive impairment.
Impairments in attention and memory are particularly evident. A large number of previous …

[HTML][HTML] Differential Serum Levels of CACNA1C, Circadian Rhythm and Stress Response Molecules in Subjects with Bipolar Disorder: Associations with Genetic and …

O Allen IV, BJ Coombes, V Pazdernik, B Gisabella… - medRxiv, 2024 - ncbi.nlm.nih.gov
Background: Many patients with bipolar disorder (BD) do not respond to or have difficulties
tolerating lithium and/or other mood stabilizing agents. There is a need for personalized …

Pleiotropic CACNA1C Variants and Neuronal Function in Psychosis

AR Docherty - Schizophrenia Bulletin, 2023 - academic.oup.com
Thanks to the ongoing global efforts of genomics consortia, genome-wide association
studies are increasingly providing common variant genetic data that may be integrated with …