Proteomics of human biological fluids for biomarker discoveries: technical advances and recent applications
L Dayon, O Cominetti, M Affolter - Expert review of proteomics, 2022 - Taylor & Francis
Introduction Biological fluids are routine samples for diagnostic testing and monitoring.
Blood samples are typically measured because of their moderate invasive collection and …
Blood samples are typically measured because of their moderate invasive collection and …
[HTML][HTML] Extracellular vesicles as therapeutic resources in the clinical environment
J Sanz-Ros, C Mas-Bargues, N Romero-García… - International journal of …, 2023 - mdpi.com
The native role of extracellular vesicles (EVs) in mediating the transfer of biomolecules
between cells has raised the possibility to use them as therapeutic vehicles. The …
between cells has raised the possibility to use them as therapeutic vehicles. The …
[HTML][HTML] Urinary extracellular vesicles: uncovering the basis of the pathological processes in kidney-related diseases
G Cricrì, L Bellucci, G Montini, F Collino - International Journal of …, 2021 - mdpi.com
Intercellular communication governs multicellular interactions in complex organisms. A
variety of mechanisms exist through which cells can communicate, eg, cell-cell contact, the …
variety of mechanisms exist through which cells can communicate, eg, cell-cell contact, the …
[HTML][HTML] Recent advances in extracellular vesicles as drug delivery systems and their potential in precision medicine
B de Jong, ER Barros, JGJ Hoenderop, JP Rigalli - Pharmaceutics, 2020 - mdpi.com
Extracellular vesicles (EVs) are membrane-bilayered nanoparticles released by most cell
types. Recently, an enormous number of studies have been published on the potential of …
types. Recently, an enormous number of studies have been published on the potential of …
[HTML][HTML] High-yield and rapid isolation of extracellular vesicles by flocculation via orbital acoustic trapping: FLOAT
Extracellular vesicles (EVs) have been identified as promising biomarkers for the
noninvasive diagnosis of various diseases. However, challenges in separating EVs from …
noninvasive diagnosis of various diseases. However, challenges in separating EVs from …
Identification of a serum and urine extracellular vesicle signature predicting renal outcome after kidney transplant
Background A long-standing effort is dedicated towards the identification of biomarkers
allowing the prediction of graft outcome after kidney transplant. Extracellular vesicles (EVs) …
allowing the prediction of graft outcome after kidney transplant. Extracellular vesicles (EVs) …
[HTML][HTML] Extracellular vesicles as drug delivery systems in organ transplantation: the next frontier
HVM Spiers, LKJ Stadler, H Smith, V Kosmoliaptsis - Pharmaceutics, 2023 - mdpi.com
Extracellular vesicles are lipid bilayer-delimited nanoparticles excreted into the extracellular
space by all cells. They carry a cargo rich in proteins, lipids and DNA, as well as a full …
space by all cells. They carry a cargo rich in proteins, lipids and DNA, as well as a full …
[HTML][HTML] Role of extracellular vesicles in pathogenesis and therapy of renal ischemia-reperfusion injury
X Zhao, Y Li, S Wu, Y Wang, B Liu, H Zhou… - Biomedicine & …, 2023 - Elsevier
Renal ischemia-reperfusion injury (RIRI) is a complex disorder characterized by both
intrinsic damage to renal tubular epithelial cells and extrinsic inflammation mediated by …
intrinsic damage to renal tubular epithelial cells and extrinsic inflammation mediated by …
[HTML][HTML] Extracellular vesicles in redox signaling and metabolic regulation in chronic kidney disease
Chronic kidney disease (CKD) is a world health problem increasing dramatically. The onset
of CKD is driven by several mechanisms; among them, metabolic reprogramming and …
of CKD is driven by several mechanisms; among them, metabolic reprogramming and …
[HTML][HTML] Saliva and Saliva extracellular vesicles for biomarker candidate Identification—assay development and pilot study in amyotrophic lateral sclerosis
S Sjoqvist, K Otake - International Journal of Molecular Sciences, 2023 - mdpi.com
Saliva is gaining increasing attention as a source of biomarkers due to non-invasive and
undemanding collection access. Extracellular vesicles (EVs) are nano-sized, cell-released …
undemanding collection access. Extracellular vesicles (EVs) are nano-sized, cell-released …