Head and neck squamous cell carcinoma (HNSCC) is a very aggressive disease with a poor
prognosis for advanced-stage tumors. Recent clinical, genomic, and cellular studies have …

Radiotherapy is one of the most common and effective therapies for cancer. Generally,
patients are treated with X-rays produced by electron accelerators. Many years ago …

In addition to the physical advantages (Bragg peak), the use of charged particles in cancer
therapy can be associated with distinct biological effects compared to X-rays. While heavy …

EGFR is a potent stimulator of invasion and metastasis in head and neck squamous cell
carcinomas (HNSCC). However, the mechanism by which EGFR may stimulate tumor cell …

The 20th century saw great advances in anatomy‐based (surgery and radiotherapy) and
chemotherapy approaches for treating head and neck squamous cell carcinoma (HNSCC) …

Squamous cell carcinoma (SCC) is an epithelial malignancy involving many anatomical
sites and is the most common cancer capable of metastatic spread. Development of early …

Inflammation plays a critical role in several diseases such as cancer, gastric, heart and
nervous system diseases. Data suggest that the activation of mammalian target of rapamycin …

Protein palmitoylation is an increasingly investigated form of post-translational lipid
modification that affects protein localization, accumulation, secretion and function. Recently …

Potentiation of epidermal growth factor receptor (EGFR) inhibitors is required in squamous
cell carcinoma of head and neck (SCCHN) to improve their therapeutic index. We …

Subpopulations of cells that escape anti-cancer treatment can cause relapse in cancer
patients. Therefore, measurements of cellular-level tumor heterogeneity could enable …