Gut microbiota dysbiosis-associated obesity and its involvement in cardiovascular diseases and type 2 diabetes. A systematic review

N Hamjane, MB Mechita, NG Nourouti, A Barakat - Microvascular Research, 2023 - Elsevier
Introduction Obesity is a complex, multifactorial disease caused by various factors. Recently,
the role of the gut microbiota in the development of obesity and its complications has …

The impact of gut microbiome-targeted therapy on liver enzymes in patients with nonalcoholic fatty liver disease: an umbrella meta-analysis

E Amini-Salehi, S Hassanipour, MH Keivanlou… - Nutrition …, 2024 - academic.oup.com
Context Nonalcoholic fatty liver disease (NAFLD) is considered the leading cause of chronic
liver disease worldwide. To date, no confirmed medication is available for the treatment of …

Identification of a gut commensal that compromises the blood pressure-lowering effect of ester angiotensin-converting enzyme inhibitors

T Yang, X Mei, E Tackie-Yarboi, MT Akere… - …, 2022 - Am Heart Assoc
Background: Despite the availability of various classes of antihypertensive medications, a
large proportion of hypertensive individuals remain resistant to treatments. The reason for …

Gut microbiota dependant trimethylamine N-oxide and hypertension

KH Mutengo, SK Masenga, A Mweemba… - Frontiers in …, 2023 - frontiersin.org
The human gut microbiota environment is constantly changing and some specific changes
influence the host's metabolic, immune, and neuroendocrine functions. Emerging evidence …

Sodium homeostasis, a balance necessary for life

A Bernal, MA Zafra, MJ Simón, J Mahía - Nutrients, 2023 - mdpi.com
Body sodium (Na) levels must be maintained within a narrow range for the correct
functioning of the organism (Na homeostasis). Na disorders include not only elevated levels …

Relationship between defecation status and blood pressure level or blood pressure variability

T Kubozono, Y Akasaki, S Kawasoe, S Ojima… - Hypertension …, 2024 - nature.com
Blood pressure variability is an independent predictor of cardiovascular disease. Defecation
status has also been associated with the risk of developing cardiovascular disease. This …

Targeting gut microbiota as a novel strategy for prevention and treatment of hypertension, atrial fibrillation and heart failure: current knowledge and future perspectives

OM Drapkina, AA Yafarova, AN Kaburova, AR Kiselev - Biomedicines, 2022 - mdpi.com
Cardiovascular diseases (CVDs) remain the major public health concern worldwide. Over
the last two decades, a considerable amount of literature has been published on gut …

Does the composition of gut microbiota affect hypertension? Molecular mechanisms involved in increasing blood pressure

J Tokarek, E Budny, M Saar, J Kućmierz… - International Journal of …, 2023 - mdpi.com
Arterial hypertension is a chronic disease which is very prevalent contemporarily. The aim of
this review was to investigate the impact of gut microbiota on the development and potential …

Protect the kidneys and save the heart using the concept of food as medicine

LFMF Cardozo, NA Borges, M Ribeiro… - Journal of Renal …, 2023 - Elsevier
Chronic kidney disease (CKD) is a significant risk factor for cardiovascular disease (CVD). In
addition to traditional risk factors, such as hypertension, dyslipidemia, diabetes and …

Constipation and high blood pressure variability

E Mishima - Hypertension Research, 2024 - nature.com
Blood pressure variability has recently gained increased attention as an independent risk
factor for adverse cardiovascular events and hypertensive target organ damage, including …