Peptide binding to MHC is critical for antigen recognition by T-cells. To facilitate vaccine
design, computational methods have been developed for predicting MHC-binding peptides …

Class II major histocompatibility complex (MHC) proteins bind peptides and present them at
the cell surface for interaction with CD4+ T cells as part of the system by which the immune …

Peptide binding induces conformational changes in class II MHC proteins that have been
characterized using a variety of hydrodynamic and spectroscopic approaches, but these …

Despite the importance of vaccinia virus in basic and applied immunology, our knowledge of
the human immune response directed against this virus is very limited. CD4+ T cell …

The work describes the development of an enrichment method for the analysis of
endogenous phosphopeptides in serum. Endogenous peptides can play significant …

HLA-DQ2 predisposes an individual to celiac sprue by presenting peptides from dietary
gluten to intestinal CD4+ T cells. A selectively deamidated multivalent peptide from gluten …

Abstract Major histocompatibility (MHC) Class II cell surface proteins present antigenic
peptides to the immune system. Class II structures in complex with peptides but not in the …

The major histocompatability complex (MHC) is a multigene family of receptors that bind and
present antigenic peptides to T‐cells. Genes of the MHC are characterized by an …

Major histocompatibility complex (MHC) class II molecules are expressed by antigen‐
presenting cells and stimulate CD 4+ T cells, which initiate humoral immune responses …

Objectives: To determine the association of DQ antigens with resistance and susceptibility to
HIV-1. Design: Despite repeated exposure to HIV-1, a subset of women in the Pumwani Sex …