[HTML][HTML] Melatonin synthesis and function: evolutionary history in animals and plants
D Zhao, Y Yu, Z Zhao, R Sharma… - Frontiers in …, 2019 - frontiersin.org
Melatonin is an ancient molecule that can be traced back to the origin of life. Melatonin's
initial function was likely that as a free radical scavenger. Melatonin presumably evolved in …
initial function was likely that as a free radical scavenger. Melatonin presumably evolved in …
Melatonin's impact on antioxidative and anti-inflammatory reprogramming in homeostasis and disease
DM Chitimus, MR Popescu, SE Voiculescu… - Biomolecules, 2020 - mdpi.com
There is a growing consensus that the antioxidant and anti-inflammatory properties of
melatonin are of great importance in preserving the body functions and homeostasis, with …
melatonin are of great importance in preserving the body functions and homeostasis, with …
Oxidative stress and inflammation in COVID-19-associated sepsis: the potential role of anti-oxidant therapy in avoiding disease progression
J Beltrán-García, R Osca-Verdegal, FV Pallardó… - Antioxidants, 2020 - mdpi.com
Since the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak
emerged, countless efforts are being made worldwide to understand the molecular …
emerged, countless efforts are being made worldwide to understand the molecular …
Pharmaceuticals targeting signaling pathways of endometriosis as potential new medical treatment: A review
Endometriosis (EM) is defined as endometrial tissues found outside the uterus. Growth and
development of endometriotic cells in ectopic sites can be promoted via multiple pathways …
development of endometriotic cells in ectopic sites can be promoted via multiple pathways …
Melatonin function and crosstalk with other phytohormones under normal and stressful conditions
Melatonin was discovered in plants in the late nineties, but its role, signaling, and crosstalk
with other phytohormones remain unknown. Research on melatonin in plants has risen …
with other phytohormones remain unknown. Research on melatonin in plants has risen …
Melatonin and its protective role against biotic stress impacts on plants
Biotic stress causes immense damage to agricultural products worldwide and raises the risk
of hunger in many areas. Plants themselves tolerate biotic stresses via several pathways …
of hunger in many areas. Plants themselves tolerate biotic stresses via several pathways …
Prophylactic melatonin for delirium in intensive care (Pro-MEDIC): a randomized controlled trial
B Wibrow, FE Martinez, E Myers, A Chapman… - Intensive Care …, 2022 - Springer
Purpose Delirium is common in the critically ill, highly distressing to patients and families
and associated with increased morbidity and mortality. Results of studies on preventative …
and associated with increased morbidity and mortality. Results of studies on preventative …
A critical review on recent trends on pharmacological applications of pyrazolone endowed derivatives
Pyrazolone is a well-known influential synthon for the synthesis of many molecules which
hold remarkable potential in the advancement of functional materials, coordination …
hold remarkable potential in the advancement of functional materials, coordination …
Efficacy and safety of anti-inflammatory agents in treatment of psychotic disorders–A comprehensive systematic review and meta-analysis
R Jeppesen, RHB Christensen, EMJ Pedersen… - Brain, behavior, and …, 2020 - Elsevier
Objective Antipsychotic effects of immunomodulating drugs have been suggested; however,
a thorough, comprehensive meta-analysis on the effect and safety of anti-inflammatory add …
a thorough, comprehensive meta-analysis on the effect and safety of anti-inflammatory add …
Therapeutic potential of melatonin related to its role as an autophagy regulator: A review
There are several pathologies, syndromes, and physiological processes in which autophagy
is involved. This process of self‐digestion that cells trigger as a survival mechanism is …
is involved. This process of self‐digestion that cells trigger as a survival mechanism is …