[HTML][HTML] Ferroptosis and its potential role in human diseases

C Han, Y Liu, R Dai, N Ismail, W Su, B Li - Frontiers in pharmacology, 2020 - frontiersin.org
Ferroptosis is a novel regulated cell death pattern discovered when studying the mechanism
of erastin-killing RAS mutant tumor cells in 2012. It is an iron-dependent programmed cell …

[HTML][HTML] Urolithin A attenuates memory impairment and neuroinflammation in APP/PS1 mice

Z Gong, J Huang, B Xu, Z Ou, L Zhang, X Lin… - Journal of …, 2019 - Springer
Background Alzheimer's disease (AD) is a progressive neurodegenerative disorder
characterized by an abnormal accumulation of amyloid-β (Aβ) plaques, neuroinflammation …

Fuel cell-based self-powered electrochemical sensors for biochemical detection

Y Chen, W Ji, K Yan, J Gao, J Zhang - Nano Energy, 2019 - Elsevier
Fuel cells (FCs) have been in development for more than 50 years; whereas the application
of weak output of some FCs in detection of biochemical species as self-powered …

Emerging roles of 5‐lipoxygenase phosphorylation in inflammation and cell death

QY Sun, HH Zhou, XY Mao - Oxidative Medicine and Cellular …, 2019 - Wiley Online Library
5‐Lipoxygenase (ALOX5) is an iron‐containing and nonheme dioxygenase that catalyzes
the peroxidation of polyunsaturated fatty acids such as arachidonic acid. ALOX5 is the rate …

Gut microbiota in Alzheimer's disease, depression, and type 2 diabetes mellitus: The role of oxidative stress

M Luca, M Di Mauro, M Di Mauro… - Oxidative medicine and …, 2019 - Wiley Online Library
Gut microbiota consists of over 100 trillion microorganisms including at least 1000 different
species of bacteria and is crucially involved in physiological and pathophysiological …

[HTML][HTML] Fatty acids: an insight into the pathogenesis of neurodegenerative diseases and therapeutic potential

DJ Vesga-Jiménez, C Martin, GE Barreto… - International journal of …, 2022 - mdpi.com
One of the most common lipids in the human body is palmitic acid (PA), a saturated fatty acid
with essential functions in brain cells. PA is used by cells as an energy source, besides …

Gut microbiome-targeted therapies for Alzheimer's disease

T Zhang, G Gao, LY Kwok, Z Sun - Gut microbes, 2023 - Taylor & Francis
The advent of highthroughput 'omics' technologies has improved our knowledge of gut
microbiome in human health and disease, including Alzheimer's disease (AD), a …

Ferroptosis: biological rust of lipid membranes

B Hassannia, S Van Coillie… - Antioxidants & Redox …, 2021 - liebertpub.com
Significance: Iron is an essential element required for growth and proper functioning of the
body. However, an excess of labile ferrous iron increases the risk of oxidative stress-induced …

The potential role of ferroptosis in Alzheimer's disease

G Zhang, Y Zhang, Y Shen, Y Wang… - Journal of …, 2021 - content.iospress.com
Alzheimer's disease (AD) is the most prevalent cause of dementia, accounting for
approximately 60%–80% of all cases. Although much effort has been made over the years …

The role of ferroptosis in neurodegenerative diseases

Y Xu, J Zhao, Y Zhao, L Zhou, H Qiao, Q Xu… - Molecular Biology …, 2023 - Springer
Ferroptosis is newly identified as a non-apoptotic form of programmed cell death. It is
characterized by iron-dependent intracellular accumulation of lipid peroxides which …