Composite outcome measures in high-impact critical care randomised controlled trials: a systematic review

HGM Walker, AJ Brown, IP Vaz, R Reed, MA Schofield… - Critical Care, 2024 - Springer
Background The use of composite outcome measures (COM) in clinical trials is increasing.
Whilst their use is associated with benefits, several limitations have been highlighted and …

The value of not intubating comatose patients with acute poisoning

Z Qasim, J Perrone, MK Delgado - JAMA, 2023 - jamanetwork.com
Imagine if a new multicenter, randomized trial of a pharmaceutical drug found that for every
3 patients treated on presentation to the hospital with a common severe illness, one …

Critical Care: What You May Have Missed in 2023

H Ajzenberg, MAN Binhashr, MK Hewitt… - Annals of Internal …, 2024 - acpjournals.org
Critical care medicine is a specialty that brings together a truly wide spectrum of patient
populations, disease states, and treatment methods. This article highlights 10 important …

[HTML][HTML] Current advances in neurocritical care

Y Chen, S Wang, S Xu, N Xu, L Zhang… - Journal of Intensive …, 2024 - Elsevier
This review summarizes the current research advances and guideline updates in
neurocritical care. For the therapy of ischemic stroke, the extended treatment time window …

Noninvasive Airway Management of Comatose Patients With Acute Poisoning—Reply

Y Freund, B Bloom - JAMA, 2024 - jamanetwork.com
To the Editor The MOMPOD study1 revealed that for pregnant individuals with preexisting
type 2 or early gestational diabetes, metformin, 1000 mg twice daily, starting before 23 …

Cost-effectiveness of non-invasive airway management of comatose patients with acute poisoning

BFN Siaha, AN Ossima, M Mimouni, Y Freund… - Intensive Care …, 2024 - Springer
The NICO (non-invasive airway management in comatose patients) randomized controlled
trial found that, in acute poisoned comatose patients with a Glasgow Coma Scale< 9 …

Noninvasive Airway Management of Comatose Patients With Acute Poisoning

CH Chiang, TY Tsai, YK Lee - JAMA, 2024 - jamanetwork.com
To the EditorWe read with great interest the recent study1 about the effect of noninvasive
airway management of comatose patients with acute poisoning, but are concerned about …

Drug users coming to European emergency departments: general basic approach and recommendations for safe discharge

G Burillo-Putze, Ò Miró - European Journal of Emergency …, 2024 - journals.lww.com
European emergency departments (EDs) have had firsthand experience in several
epidemics related to illicit drug overdose. In the 1980s, the intravenous heroin epidemic took …

Rethinking the paradigm of Glasgow Coma Scale directed intubation in poisoned comatose patients: insights from the NICO randomized controlled trial

Y Freund - European journal of emergency medicine, 2024 - journals.lww.com
The Glasgow Coma Scale (GCS) was introduced in 1974 to describe the depth of impaired
consciousness [1]. Its simplicity has enabled healthcare professionals to uniformly …

[PDF][PDF] 2022~ 2023 年神经重症进展与展望

陈雨晴, 王淑雅, 张琳琳, 周建新 - 中国急救医学 - cnemergency.org.cn
降, 但总体病死率和致残率仍较高. 该研究证实, 针对多项治疗目标的集束化方案可改善ICH
患者的神经系统功能. 1.2. 2 aSAH 的治疗进М Wolf 等[14] 进行的EARLYDRAIN …