The protein dyshomeostasis is identified as the hallmark of many age-related
neurodegenerative disorders including Parkinson's disease (PD). The diseased brain shows …

Simple Summary DNA methylation is involved in biological processes including
neurogenesis, aging, and the pathogenesis of brain disorders by the regulation of gene …

Parkinson's disease (PD) is the second most common neurodegenerative disorder with an
unclear etiology and no disease-modifying treatment to date. PD is considered a …

Neurodegenerative disorders (NDDs) are major health issues in Western countries. Despite
significant efforts, no effective therapeutics for NDDs exist. Several drugs that target …

Simple Summary The prevalence of neurodegenerative disorders has increased, yet
reliable, pre-symptomatic biomarkers for early detection and subsequent preventive …

Functional magnetic resonance imaging (fMRI) is a convolution of latent neural activity and
the hemodynamic response function (HRF). According to prior studies, the …

Goals of the investigation: This work aimed to evaluate the neuroprotective effects of zinc
oxide (ZnO) nanoparticles in an experimental mouse model of rotenone-induced PD and …

Novel and effective chemotherapeutic agents are needed to improve cancer treatment.
Epidrugs are currently used for cancer therapy but also exhibit toxicity. Targeting the …

Alzheimer's disease (AD) is characterized by beta-amyloid (Aß) plaques and
hyperphosphorylated tau containing neurofibrillary tangles (NFTs) throughout the brain. In …

Resumen Contextualización: La Enfermedad de Parkinson (EP) es la segunda enfermedad
neurodegenerativa más común en la actualidad y la que mayor crecimiento tiene a nivel …