Environmental exposures interplay with human host factors to promote the development and
progression of allergic diseases. The worldwide prevalence of allergic disease is rising as a …

Health and Clinical Impacts of Air Pollution and Linkages with Climate Change | NEJM
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Background: The persistently high prevalence of allergic diseases in Western industrial
nations and the limited possibilities of causal therapy make evidence-based …

Air pollution and climate change are potential drivers for the increasing burden of allergic
diseases. The molecular mechanisms by which air pollutants and climate parameters may …

Background Cities are home to over half the global population; that proportion is expected to
rise to 70% by mid-century. The urban environment differs greatly from that in which humans …

Lung function reference values are traditionally based on anthropometric factors, such as
weight, height, sex, and age. FVC and FEV 1 decline with age, while volumes and …

Socially disadvantaged individuals are at greater risk for simultaneously being exposed to
adverse social and environmental conditions. Although the mechanisms underlying joint …

Asthma is a heterogeneous disease that results from the complex interaction between
genetic factors and environmental exposures that occur at critical periods throughout life. It …

Background Air pollution is associated with asthma development in children and adults, but
the impact on asthma development during the transition from adolescence to adulthood is …

Résumé The rising frequency of obstructive respiratory diseases during recent years, in
particular allergic asthma, can be partially explained by changes in the environment, with …