[HTML][HTML] Progression in translational research on spinal cord injury based on microenvironment imbalance
B Fan, Z Wei, S Feng - Bone research, 2022 - nature.com
Spinal cord injury (SCI) leads to loss of motor and sensory function below the injury level
and imposes a considerable burden on patients, families, and society. Repair of the injured …
and imposes a considerable burden on patients, families, and society. Repair of the injured …
[HTML][HTML] Functional nanomaterials in peripheral nerve regeneration: scaffold design, chemical principles and microenvironmental remodeling
Y Qian, H Lin, Z Yan, J Shi, C Fan - Materials Today, 2021 - Elsevier
Neuronal microenvironment imbalance is associated with successive and irreversible
pathophysiological changes and insufficient functional restoration after peripheral nerve …
pathophysiological changes and insufficient functional restoration after peripheral nerve …
Mitochondrial dynamics in adaptive and maladaptive cellular stress responses
Mitochondria sense and respond to many stressors and can support cell survival or death
through energy production and signalling pathways. Mitochondrial responses depend on …
through energy production and signalling pathways. Mitochondrial responses depend on …
Intrinsic mechanisms of neuronal axon regeneration
M Mahar, V Cavalli - Nature Reviews Neuroscience, 2018 - nature.com
Permanent disabilities following CNS injuries result from the failure of injured axons to
regenerate and rebuild functional connections with their original targets. By contrast, injury …
regenerate and rebuild functional connections with their original targets. By contrast, injury …
[HTML][HTML] Mitostasis in neurons: maintaining mitochondria in an extended cellular architecture
T Misgeld, TL Schwarz - Neuron, 2017 - cell.com
Neurons have more extended and complex shapes than other cells and consequently face a
greater challenge in distributing and maintaining mitochondria throughout their arbors …
greater challenge in distributing and maintaining mitochondria throughout their arbors …
Cell biology of the mitochondrion
AM Van der Bliek, MM Sedensky, PG Morgan - Genetics, 2017 - academic.oup.com
Mitochondria are best known for harboring pathways involved in ATP synthesis through the
tricarboxylic acid cycle and oxidative phosphorylation. Major advances in understanding …
tricarboxylic acid cycle and oxidative phosphorylation. Major advances in understanding …
Mitochondria, energy, and metabolism in neuronal health and disease
Mitochondria are associated with various cellular activities critical to homeostasis,
particularly in the nervous system. The plastic architecture of the mitochondrial network and …
particularly in the nervous system. The plastic architecture of the mitochondrial network and …
Endoplasmic reticulum–mitochondria signaling in neurons and neurodegenerative diseases
A Markovinovic, J Greig… - Journal of Cell …, 2022 - journals.biologists.com
Recent advances have revealed common pathological changes in neurodegenerative
diseases, such as Alzheimer's disease, Parkinson's disease and amyotrophic lateral …
diseases, such as Alzheimer's disease, Parkinson's disease and amyotrophic lateral …
Axon regeneration in the central nervous system: facing the challenges from the inside
M Curcio, F Bradke - Annual review of cell and developmental …, 2018 - annualreviews.org
After an injury in the adult mammalian central nervous system (CNS), lesioned axons fail to
regenerate. This failure to regenerate contrasts with axons' remarkable potential to grow …
regenerate. This failure to regenerate contrasts with axons' remarkable potential to grow …
Pleiotropic mitochondria: the influence of mitochondria on neuronal development and disease
Mitochondria play many important biological roles, including ATP production, lipid
biogenesis, ROS regulation, and calcium clearance. In neurons, the mitochondrion is an …
biogenesis, ROS regulation, and calcium clearance. In neurons, the mitochondrion is an …