CRISPR technology: A decade of genome editing is only the beginning

JY Wang, JA Doudna - Science, 2023 - science.org
The advent of clustered regularly interspaced short palindromic repeat (CRISPR) genome
editing, coupled with advances in computing and imaging capabilities, has initiated a new …

[HTML][HTML] Genome engineering for crop improvement and future agriculture

C Gao - Cell, 2021 - cell.com
Feeding the ever-growing population is a major challenge, especially in light of rapidly
changing climate conditions. Genome editing is set to revolutionize plant breeding and …

Targeting a gene regulatory element enhances rice grain yield by decoupling panicle number and size

X Song, X Meng, H Guo, Q Cheng, Y Jing… - Nature …, 2022 - nature.com
Crop genetic improvement requires balancing complex tradeoffs caused by gene pleiotropy
and linkage drags, as exemplified by IPA1 (Ideal Plant Architecture 1), a typical pleiotropic …

Precise plant genome editing using base editors and prime editors

KA Molla, S Sretenovic, KC Bansal, Y Qi - Nature Plants, 2021 - nature.com
The development of CRISPR–Cas systems has sparked a genome editing revolution in
plant genetics and breeding. These sequence-specific RNA-guided nucleases can induce …

[HTML][HTML] Smart breeding driven by big data, artificial intelligence, and integrated genomic-enviromic prediction

Y Xu, X Zhang, H Li, H Zheng, J Zhang, MS Olsen… - Molecular Plant, 2022 - cell.com
The first paradigm of plant breeding involves direct selection-based phenotypic observation,
followed by predictive breeding using statistical models for quantitative traits constructed …

[HTML][HTML] A super pan-genomic landscape of rice

L Shang, X Li, H He, Q Yuan, Y Song, Z Wei, H Lin… - Cell Research, 2022 - nature.com
Pan-genomes from large natural populations can capture genetic diversity and reveal
genomic complexity. Using de novo long-read assembly, we generated a graph-based …

[HTML][HTML] Reap the crop wild relatives for breeding future crops

A Bohra, B Kilian, S Sivasankar, M Caccamo… - Trends in …, 2022 - cell.com
Crop wild relatives (CWRs) have provided breeders with several'game-changing'traits or
genes that have boosted crop resilience and global agricultural production. Advances in …

Rice functional genomics: decades' efforts and roads ahead

R Chen, Y Deng, Y Ding, J Guo, J Qiu, B Wang… - Science China Life …, 2022 - Springer
Rice (Oryza sativa L.) is one of the most important crops in the world. Since the completion of
rice reference genome sequences, tremendous progress has been achieved in …

[HTML][HTML] Fast-forward breeding for a food-secure world

RK Varshney, A Bohra, M Roorkiwal, R Barmukh… - Trends in Genetics, 2021 - cell.com
Crop production systems need to expand their outputs sustainably to feed a burgeoning
human population. Advances in genome sequencing technologies combined with efficient …

[HTML][HTML] The integrated genomics of crop domestication and breeding

X Huang, S Huang, B Han, J Li - Cell, 2022 - cell.com
As a major event in human civilization, wild plants were successfully domesticated to be
crops, largely owing to continuing artificial selection. Here, we summarize new discoveries …