Mitophagy is an essential mitochondrial quality control mechanism that eliminates damaged
mitochondria and the production of reactive oxygen species (ROS). The relationship …

Cardiac fibrosis (CF) is considered an ultimate common pathway of a wide variety of heart
diseases in response to diverse pathological and pathophysiological stimuli. Mitochondria …

The female ovary contains a finite number of oocytes, and their release at ovulation
becomes sporadic and disordered with aging and with obesity, leading to loss of fertility …

STUDY QUESTION Do mitochondria-targeted therapies reverse ageing-and oxidative stress-
induced spindle defects in oocytes from mice and humans? SUMMARY ANSWER Exposure …

The development of oocytes and early embryos is dependent on mitochondrial ATP
production. This reliance on mitochondrial activity, together with the exclusively maternal …

Premature ovarian insufficiency (POI) is a condition that arises from dysfunction or early
depletion of the ovarian follicle pool accompanied by an earlier-than-normal loss of fertility in …

Neurodegenerative diseases (NDDs) such as Alzheimer's disease, Parkinson's disease and
Huntington's disease (HD), amyotrophic lateral sclerosis, and prion diseases are all …

Mitochondria fragmentation destabilizes mitochondrial membranes, promotes oxidative
stress and facilitates cell death, thereby contributing to the development and the progression …

Non‐small cell lung cancer (NSCLC) is often complicated by pulmonary infection, which
affects treatment and prognosis. Bacterial lipopolysaccharide (LPS) is an effective stimulator …

While critical for male fertility preservation, cryopreservation damage reduces sperm quality
and fertilization potential. This study investigated whether the addition of mitochondrial …