Gastrointestinal cancers are a leading cause of cancer morbidity and mortality worldwide
with 4.2 million new cases and 3.2 million deaths estimated in 2020. Despite the advances …

Cancer is a major public health concern worldwide and main burden of the healthcare
system. Regrettably, most of the currently used cancer treatment approaches such as …

The extract of pomegranate (Punica granatum) has been applied in medicine since ancient
times due to its broad-spectrum health-beneficial properties. It is a rich source of …

Scorpion-venom-derived peptides have become a promising anticancer agent due to their
cytotoxicity against tumor cells via multiple mechanisms. The suppressive effect of the …

The high prevalence of neurodegenerative diseases has become a major public health
challenge and is associated with a tremendous burden on individuals, society and federal …

Curcumin, a polyphenolic compound, is a well-known anticancer agent, although its poor
bioavailability remains a big concern. Recent studies suggest that autophagy-targeted …

Natural products are well-characterized to have pharmacological or biological activities that
can be of therapeutic benefits for cancer therapy, which also provide an important source of …

Non-small cell lung cancer (NSCLC) is the leading cause of death in lung cancer due to its
aggressiveness and rapid migration. The potent antitumor effect of Smp24, an antimicrobial …

Objective: Gallbladder cancer (GBC) mortality remains high and chemoresistance is
increasing. This review consolidates what is known about the mechanisms of …

Autophagy constitutes a well-known homeostatic and catabolic process that is responsible
for degradation and recycling of cellular components. It is a key regulatory mechanism for …