[HTML][HTML] Stochastic loss and gain of symmetric divisions in the C. elegans epidermis perturbs robustness of stem cell number

D Katsanos, SL Koneru, L Mestek Boukhibar… - PLoS …, 2017 - journals.plos.org
Biological systems are subject to inherent stochasticity. Nevertheless, development is
remarkably robust, ensuring the consistency of key phenotypic traits such as correct cell …

[HTML][HTML] Co-expression networks from gene expression variability between genetically identical seedlings can reveal novel regulatory relationships

S Cortijo, M Bhattarai, JCW Locke… - Frontiers in plant …, 2020 - frontiersin.org
Co-expression networks are a powerful tool to understand gene regulation. They have been
used to identify new regulation and function of genes involved in plant development and …

Resolving the complex genetic basis of phenotypic variation and variability of cellular growth

N Ziv, BM Shuster, ML Siegal, D Gresham - Genetics, 2017 - academic.oup.com
In all organisms, the majority of traits vary continuously between individuals. Explaining the
genetic basis of quantitative trait variation requires comprehensively accounting for genetic …

[HTML][HTML] A sibling method for identifying vQTLs

D Conley, R Johnson, B Domingue, C Dawes… - PloS one, 2018 - journals.plos.org
The propensity of a trait to vary within a population may have evolutionary, ecological, or
clinical significance. In the present study we deploy sibling models to offer a novel and …

Does gene expression noise play a functional role in plants?

S Cortijo, JCW Locke - Trends in plant science, 2020 - cell.com
Gene expression in individual cells can be surprisingly noisy. In unicellular organisms this
noise can be functional; for example, by allowing a subfraction of the population to prepare …

Unveiling pepper Immunity's robustness to temperature shifts: insights for empowering future crops

W Billaud, J Hirsch, V Ribaut, L Tamisier… - Horticulture …, 2024 - academic.oup.com
Boosting plant immunity is an effective alternative to pesticides. However, environmental
variations, accentuated by climate change, can compromise immunity. The robustness of a …

[HTML][HTML] Unifying genetic canalization, genetic constraint, and genotype-by-environment interaction: QTL by genomic background by environment interaction of …

CR Lee, JT Anderson, T Mitchell-Olds - PLoS genetics, 2014 - journals.plos.org
Natural populations exhibit substantial variation in quantitative traits. A quantitative trait is
typically defined by its mean and variance, and to date most genetic mapping studies focus …

[HTML][HTML] Developmental plasticity and robustness of a nematode mouth-form polyphenism

B Sieriebriennikov, RJ Sommer - Frontiers in Genetics, 2018 - frontiersin.org
In the last decade, case studies in plants and animals provided increasing insight into the
molecular mechanisms of developmental plasticity. When complemented with evolutionary …

Ethylene‐induced hyponastic growth in Arabidopsis thaliana is controlled by ERECTA

M Van Zanten, L Basten Snoek… - The Plant …, 2010 - Wiley Online Library
Plants can respond quickly and profoundly to detrimental changes in their environment. For
example, Arabidopsis thaliana can induce an upward leaf movement response through …

Disintegrating the fly: A mutational perspective on phenotypic integration and covariation

A Haber, I Dworkin - Evolution, 2017 - academic.oup.com
The structure of environmentally induced phenotypic covariation can influence the effective
strength and magnitude of natural selection. Yet our understanding of the factors that …