Health equality, race and pharmacogenomics

EF Magavern, D Gurdasani, FL Ng… - British journal of clinical …, 2022 - Wiley Online Library
Pharmacogenomics is increasingly moving into mainstream clinical practice. Careful
consideration must be paid to inclusion of diverse populations in research, translation and …

[HTML][HTML] Advances in integrative African genomics

C Zhang, MEB Hansen, SA Tishkoff - Trends in Genetics, 2022 - cell.com
There has been a rapid increase in human genome sequencing in the past two decades,
resulting in the identification of millions of previously unknown genetic variants. However …

The INGENIOUS trial: Impact of pharmacogenetic testing on adverse events in a pragmatic clinical trial

MT Eadon, MB Rosenman, P Zhang… - The …, 2023 - nature.com
Adverse drug events (ADEs) account for a significant mortality, morbidity, and cost burden.
Pharmacogenetic testing has the potential to reduce ADEs and inefficacy. The objective of …

Toward representative genomic research: the children's rare disease cohorts experience

ZJ Frazier, E Brown, S Rockowitz… - … Advances in Rare …, 2023 - journals.sagepub.com
Background: Due to racial, cultural, and linguistic marginalization, some populations
experience disproportionate barriers to genetic testing in both clinical and research settings …

Applying an equity lens to pharmacogenetic research and translation to under‐represented populations

T Luczak, D Stenehjem, J Brown - Clinical and translational …, 2021 - Wiley Online Library
Since the publication of the Human Genome Project, genetic information has been used as
an accepted, evidence‐based biomarker to optimize patient care through the delivery of …

[HTML][HTML] Barriers to enrollment in rheumatology research: who, what, where, when, and why?

VK Sandhu, T Duro, A Kamboj, L Salto, N Chiruvolu - Cureus, 2022 - ncbi.nlm.nih.gov
Despite the evidence that complicated rheumatic diseases are more prevalent and severe in
ethnic minorities, rheumatology research is afflicted with inadequate patient representation …

Adapting a research and community capacity-building program to address rural cancer burden and facilitate partnership development between rural community …

MW Lewis-Thames, N Leahy, AJ Kruse-Diehr… - Journal of Cancer …, 2023 - Springer
While rural–urban cancer disparities persist, the research building capacity between rural
communities and high-quality cancer centers remains limited. Thus, we describe how a …

[图书][B] Identifying Racial/Ethnic Differences in Clinical Trial Enrollment, Drug Response, and Genetic Biomarkers of Taxane Induced Peripheral Neuropathy in African …

E Shah - 2021 - search.proquest.com
My first aim identified enrollment patterns and variables that predict enrollment in a diverse
underserved population and evaluated barriers to enrollment. We analyzed data from the …